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Trehalose- and Glucose-Derived Glycoamphiphiles: Small-Molecule and Nanoparticle Toll-Like Receptor 4 (TLR4) Modulators

 

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Opened Access Trehalose- and Glucose-Derived Glycoamphiphiles: Small-Molecule and Nanoparticle Toll-Like Receptor 4 (TLR4) Modulators
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Author: Rodríguez Lavado, Julio
Sestito, Stefania E.
Cighetti, Roberto
Aguilar Moncayo, Eva M.
Oblak, Alja
Lainšček, Duško
Jiménez Blanco, José Luis
García Fernández, José Manuel
Ortiz Mellet, Carmen
Jerala, Roman
Calabrese, Valentina
Peri, Francesco
Department: Universidad de Sevilla. Departamento de Química Orgánica
Date: 2014
Published in: Journal of Medicinal Chemistry, 57 (21), 9105-9123.
Document type: Article
Abstract: An increasing number of pathologies have been linked to Toll-like receptor 4 (TLR4) activation and signaling, therefore new hit and lead compounds targeting this receptor activation process are urgently needed. We report on the synthesis and biologi...
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Cite: Rodríguez Lavado, J., Sestito, S.E., Cighetti, R., Aguilar Moncayo, E.M., Oblak, A., Lainšček, D.,...,Peri, F. (2014). Trehalose- and Glucose-Derived Glycoamphiphiles: Small-Molecule and Nanoparticle Toll-Like Receptor 4 (TLR4) Modulators. Journal of Medicinal Chemistry, 57 (21), 9105-9123.
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URI: https://hdl.handle.net/11441/78585

DOI: 10.1021/jm501182w

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