Ponencia
Bioimpedance real-time charazterization of neointimal tissue inside stents
Autor/es | Rivas-Marchena, David
Olmo Fernández, Alberto Huertas Sánchez, Gloria Yúfera García, Alberto Miguel, José Ángel Martínez, Mar |
Coordinador/Director | Rueda Rueda, Adoración |
Departamento | Universidad de Sevilla. Departamento de Tecnología Electrónica Universidad de Sevilla. Departamento de Electrónica y Electromagnetismo |
Fecha de publicación | 2017 |
Fecha de depósito | 2018-09-07 |
Publicado en |
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Resumen | It is hereby presented a new approach to monitor restenosis in arteries fitted with a stent during an angioplasty. The growth of neointimal tissue is followed up by measuring its bioimpedance with Electrical Impedance ... It is hereby presented a new approach to monitor restenosis in arteries fitted with a stent during an angioplasty. The growth of neointimal tissue is followed up by measuring its bioimpedance with Electrical Impedance Spectroscopy (EIS). Besides, a mathematical model is derived to analytically describe the neointima’s histological composition from its bioimpedance. The model is validated by finite-element analysis (FEA) with COMSOL Multiphysics®. Satisfactory correlation between the analytical model and the FEA simulation is achieved for most of the characterization range, detecting some deviations introduced by the thin "double layer" that separates the neointima and the blood. It is shown how to apply conformal transformations to obtain bioimpedance models for stack-layered tissues over coplanar electrodes. Particularly, this is applied to characterize the neointima in real-time. This technique is either suitable as a main mechanism of restenosis follow-up or it can be combined with proposed blood-pressure-measuring intelligent stents to auto-calibrate the sensibility loss caused by the adherence of the tissue on the micro-electro-mechanical sensors (MEMS). |
Agencias financiadoras | Ministerio de Economia, Industria y Competitividad (MINECO). España |
Identificador del proyecto | TEC2013-46242-C3-1-P
TEC2013-46242-C3-2-P |
Cita | Rivas-Marchena, D., Olmo Fernández, A., Huertas Sánchez, G., Yúfera García, A., Miguel, J.Á. y Martínez, M. (2017). Bioimpedance real-time charazterization of neointimal tissue inside stents. En DCIS 2017 - XXXII Conference on Design of Circuits and Integrated Systems, Barcelona (España). |
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