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Deciphering of polycationic carbohydrate based non-viral gene delivery agents by ESI-LTQ-Orbitrap using CID/HCD pairwise tandem mass spectrometry

 

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Opened Access Deciphering of polycationic carbohydrate based non-viral gene delivery agents by ESI-LTQ-Orbitrap using CID/HCD pairwise tandem mass spectrometry
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Author: Przybylsk, Cédric
Benito, Juan M.
Bonnet, Véronique
Ortiz-Mellet, Carmen
García-Fernández, José Manuel
Date: 2016
Published in: RSC Advances, 6 (82), 78803-78817.
Document type: Article
Abstract: For almost three decades, gene therapy has been gaining interest to efficiently treat some severe diseases. In such context, the discovery of an efficient non-viral gene carrier to deliver genetic material into targeted cell nuclei is of prime impor...
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Cite: Przybylsk, C., Benito, J.M., Bonnet, V., Ortiz-Mellet, C. y García-Fernández, J.M. (2016). Deciphering of polycationic carbohydrate based non-viral gene delivery agents by ESI-LTQ-Orbitrap using CID/HCD pairwise tandem mass spectrometry. RSC Advances, 6 (82), 78803-78817.
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URI: https://hdl.handle.net/11441/76301

DOI: 10.1039/C6RA14508F

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