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New insights into CtIP protein: expression in breast cancer and regulation by sumoylation

 

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Opened Access New insights into CtIP protein: expression in breast cancer and regulation by sumoylation
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Author: Soria Bretones, Isabel
Director: Huertas Sánchez, Pablo
Department: Universidad de Sevilla. Departamento de Genética
Date: 2017-09-22
Document type: Doctoral Thesis
Abstract: Las roturas de doble cadena representan el tipo más nocivo entre todas las posibles lesiones que pueden ocurrir en el ADN, ya que ponen en peligro la viabilidad celular y la estabilidad genómica. Las células eucariotas han desarrollado dos vías prin...
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DNA double strand breaks (DSBs) are highly cytotoxic DNA lesions that threaten cellular viability and genomic stability. To avoid the deleterious outcomes of persistent DSBs, eukaryotic cells have developed two main repair pathways: Non homologous e...
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Cite: Soria Bretones, I. (2017). New insights into CtIP protein: expression in breast cancer and regulation by sumoylation. (Tesis Doctoral Inédita). Universidad de Sevilla, Sevilla.
Size: 104.7Mb
Format: PDF

URI: https://hdl.handle.net/11441/75859

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