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May the evaluation of nitrosative stress through selective increase of 3-nitrotyrosine proteins other than nitroalbumin and dominant tyrosine-125/136 nitrosylation of serum α-synuclein serve for diagnosis of sporadic Parkinson's disease?

 

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Opened Access May the evaluation of nitrosative stress through selective increase of 3-nitrotyrosine proteins other than nitroalbumin and dominant tyrosine-125/136 nitrosylation of serum α-synuclein serve for diagnosis of sporadic Parkinson's disease?
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Author: Fernández-Espejo, Emilio
García Moreno, José Manuel
Martín de Pablos, Ángel
Chacón, José
Department: Universidad de Sevilla. Departamento de Fisiología Médica y Biofísica
Date: 2013
Document type: Article
Abstract: Nitrosative stress, where nitrosylation of tyrosine (Tyr) leading to 3-nitrotyrosine proteins or free 3-nitrotyrosine is the most prominent change, has been proposed as a pathogenic mechanism in Parkinson's disease (PD). Levels of 3-nitrotyrosine pr...
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URI: https://hdl.handle.net/11441/75280

DOI: 10.1089/ars.2013.5250

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