Repositorio de producción científica de la Universidad de Sevilla

New Arabidopsis thaliana cytochrome c partners: A look into the elusive role of cytochrome c in programmed cell death in plants

Opened Access New Arabidopsis thaliana cytochrome c partners: A look into the elusive role of cytochrome c in programmed cell death in plants

Citas

buscar en

Estadísticas
Icon
Exportar a
Autor: Martínez Fábregas, Jonathan
Díaz Moreno, Irene
González Arzola, Katiuska
Janocha, Simon
Navarro Carruesco, José Antonio
Hervás Morón, Manuel
Bernhardt, Rita
Díaz Quintana, Antonio Jesús
Rosa Acosta, Miguel Ángel de la
Departamento: Universidad de Sevilla. Departamento de Bioquímica Vegetal y Biología Molecular
Fecha: 2013
Publicado en: Molecular and Cellular Proteomics, 12 (12), 3666-3676.
Tipo de documento: Artículo
Resumen: Programmed cell death is an event displayed by many different organisms along the evolutionary scale. In plants, programmed cell death is necessary for development and the hypersensitive response to stress or pathogenic infection. A common feature in programmed cell death across organisms is the translocation of cytochrome c from mitochondria to the cytosol. To better understand the role of cytochrome c in the onset of programmed cell death in plants, a proteomic approach was developed based on affinity chromatography and using Arabidopsis thaliana cytochrome c as bait. Using this approach, ten putative new cytochrome c partners were identified. Of these putative partners and as indicated by bimolecular fluorescence complementation, nine of them bind the heme protein in plant protoplasts and human cells as a heterologous system. The in vitro interaction between cytochrome c and such soluble cytochrome c-targets was further corroborated using surface plasmon resonance. Taken together, ...
[Ver más]
Cita: Martínez Fábregas, J., Díaz Moreno, I., González Arzola, K., Janocha, S., Navarro Carruesco, J.A., Hervás Morón, M.,...,Rosa Acosta, M.Á.d.l. (2013). New Arabidopsis thaliana cytochrome c partners: A look into the elusive role of cytochrome c in programmed cell death in plants. Molecular and Cellular Proteomics, 12 (12), 3666-3676.
Tamaño: 685.8Kb
Formato: PDF

URI: https://hdl.handle.net/11441/70250

DOI: 10.1074/mcp.M113.030692

Ver versión del editor

Mostrar el registro completo del ítem


Esta obra está bajo una Licencia Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 Internacional

Este registro aparece en las siguientes colecciones