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CSPα-deficiency causes massive and rapid photoreceptor degeneration

 

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Opened Access CSPα-deficiency causes massive and rapid photoreceptor degeneration
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Author: Schmitz, Frank
Tabares Domínguez, Lucía
Khimich, Darina
Strenzke, Nicola
Villa Polo, Pedro de la
Castellano Muñoz, Manuel
Bulankina, Anna
Moser, Tobias
Fernández-Chacón, Rafael
Südhof, Thomas C.
Department: Universidad de Sevilla. Departamento de Fisiología Médica y Biofísica
Date: 2006
Published in: Proceedings of the National Academy of Sciences of the United States of America, 103 (8), 2926-2931.
Document type: Article
Abstract: Cysteine string protein (CSP) α is an abundant synaptic vesicle protein that contains a DNA-J domain characteristic of Hsp40-type cochaperones. Previous studies showed that deletion of CSPα in mice leads to massive lethal neurodegeneration but did n...
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Cite: Schmitz, F., Tabares Domínguez, L., Khimich, D., Strenzke, N., Villa Polo, P.d.l., Castellano Muñoz, M.,...,Südhof, T.C. (2006). CSPα-deficiency causes massive and rapid photoreceptor degeneration. Proceedings of the National Academy of Sciences of the United States of America, 103 (8), 2926-2931.
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URI: https://hdl.handle.net/11441/69842

DOI: 10.1073/pnas.0510060103

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