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Insulin Reverses D-Glucose–Increased Nitric Oxide and Reactive Oxygen Species Generation in Human Umbilical Vein Endothelial Cells

 

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Opened Access Insulin Reverses D-Glucose–Increased Nitric Oxide and Reactive Oxygen Species Generation in Human Umbilical Vein Endothelial Cells
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Author: González, Marcelo
Rojas, Susana
Avila, Pía
Cabrera, Lissette
Villalobos, Roberto
Palma, Carlos
Aguayo, Claudio
Sobrevia Luarte, Luis
Department: Universidad de Sevilla. Departamento de Fisiología
Date: 2015
Published in: Plos One, 10 (4), 1-23.
Document type: Article
Abstract: Vascular tone is controlled by the L-arginine/nitric oxide (NO) pathway, and NO bioavailability is strongly affected by hyperglycaemia-induced oxidative stress. Insulin leads to high expression and activity of human cationic amino acid transporter 1...
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Cite: González, M., Rojas, S., Avila, P., Cabrera, L., Villalobos, ., Palma, C.,...,Sobrevia Luarte, L. (2015). Insulin Reverses D-Glucose–Increased Nitric Oxide and Reactive Oxygen Species Generation in Human Umbilical Vein Endothelial Cells. Plos One, 10 (4), 1-23.
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URI: http://hdl.handle.net/11441/67632

DOI: 10.1371/journal.pone.0122398

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