Repositorio de producción científica de la Universidad de Sevilla

Uptake and intracellular activity of linezolid in human phagocytes and nonphagocytic cells

Opened Access Uptake and intracellular activity of linezolid in human phagocytes and nonphagocytic cells

Citas

buscar en

Estadísticas
Icon
Exportar a
Autor: Pascual Hernández, Álvaro
Ballesta Mudarra, Sofía
García Luque, Isabel
Perea Pérez, Evelio José
Departamento: Universidad de Sevilla. Departamento de Microbiología
Fecha: 2002-12-01
Publicado en: Antimicrobial Agents and Chemotherapy, 46 (12), 4013-4015.
Tipo de documento: Artículo
Resumen: The intracellular penetration and activity of linezolid in human polymorphonuclear leukocytes and tissue-cultured cells (McCoy) were evaluated. Linezolid reached intracellular concentrations slightly greater than extracellular ones in both types of cell. The uptake was rapid and not saturable and was affected by environmental temperature and cell viability. Linezolid showed slight intracellular activity against Staphylococcus epidermidis at high extracellular concentrations.
Cita: Pascual Hernández, Á., Ballesta Mudarra, S., García Luque, I. y Perea Pérez, E.J. (2002). Uptake and intracellular activity of linezolid in human phagocytes and nonphagocytic cells. Antimicrobial Agents and Chemotherapy, 46 (12), 4013-4015.
Tamaño: 64.11Kb
Formato: PDF

URI: http://hdl.handle.net/11441/65004

DOI: 10.1128/AAC.46.12.4013-4015.2002

Ver versión del editor

Mostrar el registro completo del ítem


Esta obra está bajo una Licencia Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 Internacional

Este registro aparece en las siguientes colecciones