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Activities of ABT-773 against Listeria monocytogenes and coryneform bacteria of clinical interest

 

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Opened Access Activities of ABT-773 against Listeria monocytogenes and coryneform bacteria of clinical interest
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Author: Conejo Gonzalo, Mª Carmen
Martínez Martínez, Luis
Pascual Hernández, Álvaro
Suárez, Ana Isabel
Perea Pérez, Evelio José
Department: Universidad de Sevilla. Departamento de Microbiología
Date: 2003-04-01
Published in: Antimicrobial Agents and Chemotherapy, 47 (4), 1403-1406.
Document type: Article
Abstract: The in vitro activities of ABT-773 were evaluated against 15 Listeria monocytogenes strains and 196 coryneform bacteria isolated from clinical samples. One hundred percent of the L. monocytogenes strains were inhibited by ≤0.015 μg of ABT-773/ml. MICs of ABT-773 (μg/ml) at which 50% of the isolates tested were inhibited (MIC50s) and MIC90s for other organisms were 0.125 and 0.5 (Corynebacterium amycolatum), 1 and >32 (Corynebacterium jeikeium), 0.03 and >32 (Corynebacterium minutissimum), >32 and >32 (Corynebacterium pseudodiphtheriticum and Corynebacterium urealyticum), 0.125 and >32 (Corynebacterium striatum), and 0.03 and 0.5 (Rhodococcus equi), respectively.
Cite: Conejo Gonzalo, M.C., Martínez Martínez, L., Pascual Hernández, Á., Suárez, A.I. y Perea Pérez, E.J. (2003). Activities of ABT-773 against Listeria monocytogenes and coryneform bacteria of clinical interest. Antimicrobial Agents and Chemotherapy, 47 (4), 1403-1406.
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URI: http://hdl.handle.net/11441/64845

DOI: 10.1128/AAC.47.4.1403-1406.2003

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