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Measurement of β+ emitters production cross sections of interest for range verification in proton therapy

Opened Access Measurement of β+ emitters production cross sections of interest for range verification in proton therapy
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Autor: Saiz Lomas, Juan
Director: Guerrero Sánchez, Carlos
Jiménez Ramos, María del Carmen
Departamento: Universidad de Sevilla. Departamento de Física Atómica, Molecular y Nuclear
Fecha: 2017-06
Tipo de documento: Trabajo Fin de Master
Titulación: Universidad de Sevilla. Máster en Física Nuclear
Resumen: The uncertainty in the dose curve delivered during the treatment of tumors with protons, i.e. the position of the Bragg peak, makes it necessary to apply safety margins from 1% to 3% in the beam range. This means nearly 1 cm in a 30 cm deep tumor, which certainly limits the benefits of having a sharp Bragg peak. Reducing this uncertainty would allow a reduction of the treatment volume and thus result in a better utilization of the advantages of protons compared to conventional radiotherapy. Among the diferent techniques that are being proposed for range verification, some of which have already been clinically tested), the measurement of the distribution of β+ radioactive nuclei (known as PET isotopes) produced by the proton beam along its path allows detecting variations of only a few millimeters in the proton beam range. For this purpose, a better database of production cross sections of β+ emitters as function of the energy of the incident proton for a wide range of elements pre...
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Cita: Saiz Lomas, J. (2017). Measurement of β+ emitters production cross sections of interest for range verification in proton therapy. (Trabajo Fin de Máster Inédito). Universidad de Sevilla, Sevilla.
Tamaño: 20.08Mb
Formato: PDF

URI: http://hdl.handle.net/11441/64680

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