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Generation of a Vero-Based Packaging Cell Line to Produce SV40 Gene Delivery Vectors for Use in Clinical Gene Therapy Studies

 

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Opened Access Generation of a Vero-Based Packaging Cell Line to Produce SV40 Gene Delivery Vectors for Use in Clinical Gene Therapy Studies
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Author: Toscano, Miguel G.
Velden, Jeroen van der
Werf, Sybrand van der
Odijk, Machteld
Camacho García, Rafael J.
Herrera Gómez, Irene G.
Department: Universidad de Sevilla. Departamento de Fisiología Médica y Biofísica
Date: 2017
Published in: Molecular Therapy - Methods and Clinical Development, 6, 124-134.
Document type: Article
Abstract: Replication-defective (RD) recombinant simian virus 40 (SV40)-based gene delivery vectors hold a great potential for clinical applications because of their presumed non-immunogenicity and capacity to induce immune tolerance to the transgene products...
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Cite: Toscano, M.G., Velden, J.v.d., Werf, S.v.d., Odijk, M., Camacho García, R.J. y Herrera Gómez, I.G. (2017). Generation of a Vero-Based Packaging Cell Line to Produce SV40 Gene Delivery Vectors for Use in Clinical Gene Therapy Studies. Molecular Therapy - Methods and Clinical Development, 6, 124-134.
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URI: http://hdl.handle.net/11441/63908

DOI: 10.1016/j.omtm.2017.06.007

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