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The cannabinoid ligand LH-21 reduces anxiety and improves glucose handling in diet-induced obese pre-diabetic mice

 

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Opened Access The cannabinoid ligand LH-21 reduces anxiety and improves glucose handling in diet-induced obese pre-diabetic mice
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Author: Romero Zerbo, Silvana Y.
Ruz Maldonado, Inmaculada
Espinosa Jiménez, Vanesa
Cobo Vuilleumier, Nadia
Gauthier, Benoit R.
Date: 2017
Published in: Scientific Reports, 7 (3946)
Document type: Article
Abstract: LH-21 is a triazol derivative that has been described as a low-permeant neutral CB1 antagonist, though its pharmacology is still unclear. It has been associated with anti-obesity actions in obese rats. However, its role in preventing type 2 diabetes...
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Cite: Romero Zerbo, S.Y., Ruz Maldonado, I., Espinosa Jiménez, V., Cobo Vuilleumier, N. y Gauthier, B.R. (2017). The cannabinoid ligand LH-21 reduces anxiety and improves glucose handling in diet-induced obese pre-diabetic mice. Scientific Reports, 7 (3946)
Size: 7.064Mb
Format: PDF

URI: http://hdl.handle.net/11441/63798

DOI: 10.1038/s41598-017-03292-w

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