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Conditional deletion of WT1 in the septum transversum mesenchyme causes congenital diaphragmatic hernia in mice

 

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Opened Access Conditional deletion of WT1 in the septum transversum mesenchyme causes congenital diaphragmatic hernia in mice
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Author: Carmona, Rita
Cañete, Ana
Cano, Elena
Ariza, Laura
Rojas, Anabel
Muñoz Chápuli, Ramón
Date: 2016
Published in: eLife, 5 (e16009), 1-17.
Document type: Article
Abstract: Congenital diaphragmatic hernia (CDH) is a severe birth defect. Wt1-null mouse embryos develop CDH but the mechanisms regulated by WT1 are unknown. We have generated a murine model with conditional deletion of WT1 in the lateral plate mesoderm, usin...
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Cite: Carmona, R., Cañete, A., Cano, E., Ariza, L., Rojas, A. y Muñoz Chápuli, R. (2016). Conditional deletion of WT1 in the septum transversum mesenchyme causes congenital diaphragmatic hernia in mice. eLife, 5 (e16009), 1-17.
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URI: http://hdl.handle.net/11441/63666

DOI: 10.7554/eLife.16009

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