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A TolC-like protein is required for heterocyst development in anabaena sp. strain PCC 7120


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dc.creator Moslavac, Suncana es
dc.creator Nicolaisen, Kerstin es
dc.creator Mirus, Oliver es
dc.creator Al Dehni, Fadi es
dc.creator Pernil, Rafael es
dc.creator Flores García, Enrique es
dc.creator Maldener, Iris es
dc.creator Schleiff, Enrico es 2017-07-25T11:41:02Z 2017-07-25T11:41:02Z 2007
dc.identifier.citation Moslavac, S., Nicolaisen, K., Mirus, O., Al Dehni, F., Pernil, R., Flores García, E.,...,Schleiff, E. (2007). A TolC-like protein is required for heterocyst development in anabaena sp. strain PCC 7120. Journal of Bacteriology, 189 (21), 7887-7895.
dc.identifier.issn 0021-9193 (impreso) es
dc.identifier.issn 1098-5530 (electronico) es
dc.description.abstract The filamentous cyanobacterium Anabaena sp. strain PCC 7120 forms heterocysts in a semiregular pattern when it is grown on N2 as the sole nitrogen source. The transition from vegetative cells to heterocysts requires marked metabolic and morphological changes. We show that a trimeric pore-forming outer membrane β-barrel protein belonging to the TolC family, Alr2887, is up-regulated in developing heterocysts and is essential for diazotrophic growth. Mutants defective in Alr2887 did not form the specific glycolipid layer of the heterocyst cell wall, which is necessary to protect nitrogenase from external oxygen. Comparison of the glycolipid contents of wild-type and mutant cells indicated that the protein is not involved in the synthesis of glycolipids but might instead serve as an exporter for the glycolipid moieties or enzymes involved in glycolipid attachment. We propose that Alr2887, together with an ABC transporter like DevBCA, is part of a protein export system essential for assembly of the heterocyst glycolipid layer. We designate the alr2887 gene hgdD (heterocyst glycolipid deposition protein). es
dc.description.sponsorship Ministerio de Educación y Ciencia BFU2005-07672 es
dc.format application/pdf es
dc.language.iso eng es
dc.publisher American Society for Microbiology es
dc.relation.ispartof Journal of Bacteriology, 189 (21), 7887-7895.
dc.rights Attribution-NonCommercial-NoDerivatives 4.0 Internacional *
dc.rights.uri *
dc.title A TolC-like protein is required for heterocyst development in anabaena sp. strain PCC 7120 es
dc.type info:eu-repo/semantics/article es
dc.type.version info:eu-repo/semantics/publishedVersion es
dc.rights.accessrights info:eu-repo/semantics/openAccess es
dc.contributor.affiliation Universidad de Sevilla. Departamento de Bioquímica Vegetal y Biología Molecular es
dc.relation.projectID BFU2005-07672 es
dc.relation.publisherversion es
dc.identifier.doi 10.1128/JB.00750-07 es
idus.format.extent 9 p. es
dc.journaltitle Journal of Bacteriology es
dc.publication.volumen 189 es
dc.publication.issue 21 es
dc.publication.initialPage 7887 es
dc.publication.endPage 7895 es
dc.contributor.funder Ministerio de Educación y Ciencia (MEC). España
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