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Role of age and sex in the diagnosis of early-stage malignant melanoma: A cross-sectional study

 

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Opened Access Role of age and sex in the diagnosis of early-stage malignant melanoma: A cross-sectional study
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Author: Moreno Ramírez, David
Ojeda-Vila,Teresa
Ríos Martín, Juan José
Nieto García, María Adoración
Ferrandiz, Lara
Department: Universidad de Sevilla. Departamento de Medicina
Universidad de Sevilla. Departamento de Citología e Histología Normal y Patológica
Universidad de Sevilla. Departamento de Medicina Preventiva y Salud Pública
Date: 2015-01
Published in: Acta Dermato-Venereologica, 95 (8), 940-942.
Document type: Article
Abstract: Age and sex have been identified as predictors of outcome in malignant melanoma (MM). The aim of this multicentre, cross-sectional study was to analyse the role of age and sex as explanatory variables for the diagnosis of thin MM. A total of 2,430 patients with MM were recruited. Cases of in situ (Tis) and T1 MM were more frequent than T2–T4 MM (56.26% vs. 43.74%). Breslow thickness increased throughout decades of life (analysis of variance (ANOVA) p < 0.001), with a weak correlation between Breslow thickness and patient's age (r = 0.202, p < 0.001). Breslow thickness was significantly less in women (1.79 vs. 2.38 mm, p = 0.0001). Binary logistic regression showed a significant (p < 0.001) odds ratio for age 0–29 years (1.18), and 30–59 years (1.16), and for women (1.09). Age and sex explained 3.64% of the variation observed in Tis–T1 frequency (R2 = 0.0364). Age and sex appear to explain a low percentage of the variation in the early detection of MM.
Cite: Moreno Ramírez, D., Ojeda-Vila, e., Ríos Martín, J.J., Nieto García, M.A. y Ferrandiz, L. (2015). Role of age and sex in the diagnosis of early-stage malignant melanoma: A cross-sectional study. Acta Dermato-Venereologica, 95 (8), 940-942.
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URI: http://hdl.handle.net/11441/62887

DOI: 10.2340/00015555-2115

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