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The HERC2 ubiquitin ligase is essential for embryonic development and regulates motor coordination

 

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Opened Access The HERC2 ubiquitin ligase is essential for embryonic development and regulates motor coordination
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Author: Ruiz Laza, Rocío
Cubillos Rojas, Mónica
Schneider,Taiane
Hadjebi, Ouadah
Department: Universidad de Sevilla. Departamento de Bioquímica y Biología Molecular
Date: 2016
Published in: Oncotarget, 7 (35), 56083-56106.
Document type: Article
Abstract: A mutation in the HERC2 gene has been linked to a severe neurodevelopmental disorder with similarities to the Angelman syndrome. This gene codifies a protein with ubiquitin ligase activity that regulates the activity of tumor protein p53 and is invo...
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Cite: Ruiz Laza, R., Cubillos Rojas, M., Schneider, a. y Hadjebi, O. (2016). The HERC2 ubiquitin ligase is essential for embryonic development and regulates motor coordination. Oncotarget, 7 (35), 56083-56106.
Size: 14.96Mb
Format: PDF

URI: http://hdl.handle.net/11441/61386

DOI: 10.18632/oncotarget.11270.

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