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Palisade Endings Are a Constant Feature in the Extraocular Muscles of Frontal-Eyed, But Not Lateral-Eyed, Animals


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dc.creator Blumer, Roland es
dc.creator Maurer-Gesek, Barbara es
dc.creator Gesslbauer, Bernhard es
dc.creator Blumer, Michael es
dc.creator Davis López de Carrizosa, María América es
dc.creator Pastor Loro, Ángel Manuel es 2017-04-28T10:11:33Z 2017-04-28T10:11:33Z 2016
dc.identifier.citation Blumer, R., Maurer-Gesek, B., Gesslbauer, ., Blumer, M., Davis López de Carrizosa, M.A. y Pastor Loro, Á.M. (2016). Palisade Endings Are a Constant Feature in the Extraocular Muscles of Frontal-Eyed, But Not Lateral-Eyed, Animals. Investigative Ophthalmology & Visual Science, 57 (2), 320-331.
dc.identifier.issn 0146-0404 es
dc.description.abstract Purpose To test whether palisade endings are a general feature of mammalian extraocular muscles (EOMs). Methods Thirteen species, some frontal-eyed (human, monkey, cat, and ferret), and others lateral-eyed (pig, sheep, calf, horse, rabbit, rat, mouse, gerbil, and guinea pig) were analyzed. Palisade endings were labeled by using different combinations of immunofluorescence techniques. Three-dimensional reconstructions of immunolabeled palisade endings were done. Results In all frontal-eyed species, palisade endings were a consistent feature in the rectus EOMs. Their total number was high and they exhibited an EOM-specific distribution. In particular, the number of palisade endings in the medial recti was significantly higher than in the other rectus muscles. In the lateral-eyed animals, palisade endings were infrequent and, when present, their total number was rather low. They were only found in ungulates (sheep, calf, pig, and horse) and in rabbit. In rodents (rat, guinea pig, mouse, and gerbil) palisade endings were found infrequently (e.g., rat) or were completely absent. Palisade endings in frontal-eyed species and in some lateral-eyed species (pig, sheep, calf, and horse) had a uniform morphology. They generally lacked α-bungarotoxin staining, with a few exceptions in primates. Palisade endings in other lateral-eyed species (rabbit and rat) exhibited a simplified morphology and bound α-bungarotoxin. Conclusions Palisade endings are not a universal feature of mammalian EOMs. So, if they are proprioceptors, not all species require them. Because in frontal-eyed species, the medial rectus muscle has the highest number of palisade endings, they likely play a special role in convergence. es
dc.format application/pdf es
dc.language.iso eng es
dc.publisher Association for Research in Vision and Ophthalmology es
dc.relation.ispartof Investigative Ophthalmology & Visual Science, 57 (2), 320-331.
dc.rights Attribution-NonCommercial-NoDerivatives 4.0 Internacional *
dc.rights.uri *
dc.subject oculomotor system es
dc.subject proprioception es
dc.subject frontal-eyed species es
dc.subject palisade endings es
dc.subject convergence es
dc.subject lateral-eyed species es
dc.title Palisade Endings Are a Constant Feature in the Extraocular Muscles of Frontal-Eyed, But Not Lateral-Eyed, Animals es
dc.type info:eu-repo/semantics/article es
dc.type.version info:eu-repo/semantics/publishedVersion es
dc.rights.accessrights info:eu-repo/semantics/openAccess es
dc.contributor.affiliation Universidad de Sevilla. Departamento de Fisiología es
dc.relation.publisherversion es
dc.identifier.doi 10.1167/iovs.15-18716 es
idus.format.extent 11 p. es
dc.journaltitle Investigative Ophthalmology & Visual Science es
dc.publication.volumen 57 es
dc.publication.issue 2 es
dc.publication.initialPage 320 es
dc.publication.endPage 331 es
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