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Escherichia coli heat-stable enterotoxin mediates Na+/H+ exchanger 4 inhibition involving cAMP in T84 human intestinal epithelial cells

 

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Opened Access Escherichia coli heat-stable enterotoxin mediates Na+/H+ exchanger 4 inhibition involving cAMP in T84 human intestinal epithelial cells
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Author: Beltrán, Ana R.
Camarro Lacroix, Luciene R.
Cornejo, Marcelo
Norambuena, Katrina
Toledo, Fernando
Pardos, Fabián
Leiva Mendoza, Andrea
Sobrevia Luarte, Luis
Ramírez, Marco Antonio
Department: Universidad de Sevilla. Departamento de Fisiología
Date: 2015
Published in: Plos One, 10 (12), e0146042-1-e0146042-15.
Document type: Article
Abstract: The enterotoxigenic Escherichia coli strains lead to diarrhoea in humans due to heat-labile and heat-stable (STa) enterotoxins. STa increases Cl-release in intestinal cells, including the human colonic carcinoma T84 cell line, involving increased cG...
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Cite: Beltrán, A.R., Camarro Lacroix, L.R., Cornejo, M., Norambuena, K., Toledo, F., Pardos, F.,...,Ramírez, M.A. (2015). Escherichia coli heat-stable enterotoxin mediates Na+/H+ exchanger 4 inhibition involving cAMP in T84 human intestinal epithelial cells. Plos One, 10 (12), e0146042-1-e0146042-15.
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URI: http://hdl.handle.net/11441/55923

DOI: 10.1371/journal.pone.0146042

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