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Inflammatory response in the hippocampus of PS1M146L/APP 751SL mouse model of Alzheimer's disease: Age-dependent switch in the microglial phenotype from alternative to classic

 

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Opened Access Inflammatory response in the hippocampus of PS1M146L/APP 751SL mouse model of Alzheimer's disease: Age-dependent switch in the microglial phenotype from alternative to classic
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Autor: Jiménez, Sebastián
Baglietto-Vargas, David
Caballero, Cristina M.
Moreno González, Inés
Vitorica Ferrández, Francisco Javier
Departamento: Universidad de Sevilla. Departamento de Bioquímica y Biología Molecular
Fecha: 2008
Publicado en: Journal of Neuroscience, 28 (45), 11650-11661.
Tipo de documento: Artículo
Resumen: Although the microglial activation is concomitant to the Alzheimer's disease, its precise role (neuroprotection vs neurodegeneration) has not yet been resolved. Here, we show the existence of an age-dependent phenotypic change of microglial activati...
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Cita: Jiménez, S., Baglietto-Vargas, D., Caballero, C.M., Moreno González, I. y Vitorica Ferrández, F.J. (2008). Inflammatory response in the hippocampus of PS1M146L/APP 751SL mouse model of Alzheimer's disease: Age-dependent switch in the microglial phenotype from alternative to classic. Journal of Neuroscience, 28 (45), 11650-11661.
Tamaño: 549.7Kb
Formato: PDF

URI: http://hdl.handle.net/11441/50003

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