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Predictive second cancer risk models based on peripheral neutron dosimetry of patients undergoing radiotherapy

Opened Access Predictive second cancer risk models based on peripheral neutron dosimetry of patients undergoing radiotherapy
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Autor: Irazola Rosales, Leticia
Director: Sánchez Doblado, Francisco
Terrón León, José Antonio
Departamento: Universidad de Sevilla. Departamento de Fisiología Médica y Biofísica
Fecha: 2016-09-16
Tipo de documento: Tesis Doctoral
Resumen: The study of Secondary Malignant Neoplasms (SMNs) after radiotherapy is becoming a topic of interest nowadays, as a consequence of the higher healing rates and life expectancy accomplished with current diagnose procedures and radiotherapy treatments. In the case of modern techniques, there is a tendency to prefer low (i.e. 6 MV) energies to high ones (e.g. 15 or 18 MV), sometimes to the detriment of treatment conformity, as the latter are known to increase equivalent dose to patients due to neutron production. The Medical Physics Group of the University of Seville, pioneered the development of a simple and universal methodology for the estimation of peripheral neutron doses, based on the correlation between readings of a SRAM-based detector (in a reference location, far from the patient) and those of passive detectors, located inside an adult anthropomorphic phantom. This correspondence model directly links detector readings (referring to thermal neutron fluence in the room) to equi...
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Cita: Irazola Rosales, L. (2016). Predictive second cancer risk models based on peripheral neutron dosimetry of patients undergoing radiotherapy. (Tesis doctoral inédita). Universidad de Sevilla, Sevilla.
Tamaño: 6.988Mb
Formato: PDF

URI: http://hdl.handle.net/11441/47106

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