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Effects of antioxidant supplementation on duodenal se-met absorption in ethanol-exposed rat offspring in vivo

Opened Access Effects of antioxidant supplementation on duodenal se-met absorption in ethanol-exposed rat offspring in vivo

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Autor: Nogales Bueno, Fátima
Ojeda Murillo, María Luisa
Delgado Guerrero, María Josefa
Jotty, Karick
Díaz Castro, Javier
Murillo Taravillo, María Luisa
Carreras Sánchez, Olimpia
Departamento: Universidad de Sevilla. Departamento de Fisiología
Fecha: 2011
Publicado en: Journal of Reproduction and Development, 57 (6), 708-714.
Tipo de documento: Artículo
Resumen: The nutritional deficiencies provoked by ethanol consumption, during gestation or lactation, can contribute to multiple birth defects in offspring. In order to improve our knowledge about selenium (Se) distribution in pups exposed to ethanol, the present study evaluated the effect of this drug on intestinal development and determined its action on duodenal absorption of selenomethionine (Se-Met). To determinate if supplementation could improve Se absorption and its serum values, we used two antioxidant supplemented regimens on dams, with selenium alone or selenium plus folic acid, and obtained six groups of pups: C (control), A (alcohol), CS (control + Se), AS (alcohol + Se), CFS (control + Se + folic acid) and AFS (alcohol + Se + folic acid). Duodenal Se-Met transport was performed using an in vivo perfusion method. Se levels were measured by graphite furnace atomic absorption spectrometry. The supplemented diets utilized had a positive influence on body growth, duodenal perimeter an...
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Cita: Nogales Bueno, F., Ojeda Murillo, M.L., Delgado Guerrero, M.J., Jotty, K., Díaz Castro, J., Murillo Taravillo, M.L. y Carreras Sánchez, O. (2011). Effects of antioxidant supplementation on duodenal se-met absorption in ethanol-exposed rat offspring in vivo. Journal of Reproduction and Development, 57 (6), 708-714.
Tamaño: 587.7Kb
Formato: PDF

URI: http://hdl.handle.net/11441/47046

DOI: 10.1262/jrd.11-049K

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