Repositorio de producción científica de la Universidad de Sevilla

Does the dynamics of sine–Gordon solitons predict active regions of DNA?

Opened Access Does the dynamics of sine–Gordon solitons predict active regions of DNA?

Citas

buscar en

Estadísticas
Icon
Exportar a
Autor: Cuenda, Sara
Sánchez, Angel
Quintero, Niurka R.
Departamento: Universidad de Sevilla. Departamento de Física Aplicada I
Fecha: 2006
Publicado en: Physica D: Nonlinear Phenomena, 223 (2), 214-221.
Tipo de documento: Artículo
Resumen: In this work we analyze the possibility that the soliton dynamics in a simple nonlinear model allows functionally relevant predictions of the behaviour of DNA. This suggestion was first put forward by Salerno [M. Salerno, Phys. Rev. A 44 (1991) 5292] by showing results indicating that sine–Gordon kinks were set in motion at certain regions of a DNA sequence that include promoters. We revisit that system and show that the observed behaviour has nothing to do with promoters; on the contrary, it originates from the bases at the boundary, which are not part of the genome studied. We explain this phenomenology in terms of an effective potential for the kink center. This is further extended to disprove recent claims that the dynamics of kinks [E. Lennholm, M. H¨ornquist, Physica D 177 (2003) 233] or breathers [J.D. Bashford, J. Biol. Phys. 32 (2006) 27] has functional significance.We conclude that no such information can be extracted from this simple nonlinear model or its associated ...
[Ver más]
Cita: Cuenda, S., Sánchez, A. y Quintero, N.R. (2006). Does the dynamics of sine–Gordon solitons predict active regions of DNA?. Physica D: Nonlinear Phenomena, 223 (2), 214-221.
Tamaño: 570.0Kb
Formato: PDF

URI: http://hdl.handle.net/11441/42458

DOI: 10.1016/j.physd.2006.09.005

Ver versión del editor

Mostrar el registro completo del ítem


Esta obra está bajo una Licencia Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 Internacional

Este registro aparece en las siguientes colecciones