Repositorio de producción científica de la Universidad de Sevilla

Confonnations in crystals and solutions of d(CACGTG), d(CCGCGG) and d(GGCGCC) studied by vibrational spectroscopy

Opened Access Confonnations in crystals and solutions of d(CACGTG), d(CCGCGG) and d(GGCGCC) studied by vibrational spectroscopy

Citas

buscar en

Estadísticas
Icon
Exportar a
Autor: Urpi, L.
Ridouxl, J.P.
Liquier, J.
Verdaguer, N.
Fita. I.
Subirana, J.A.
Iglesias Guerra, Fernando
Huynh-Dinh, T.
lgolen, J.
Taillandier, E.
Departamento: Universidad de Sevilla. Departamento de Química Orgánica y Farmacéutica
Fecha: 1989
Publicado en: Nucleic Acids Research, 17 (16), 6669-6680.
Tipo de documento: Artículo
Resumen: Crystals of self camplementary DMA hexamers dCCACGTG>, dCCCGCGG> and d<GGCGCC> were grown bf vapour dlffuslon technlque and studled by mlcroRaman and mlcroiR spectroscop es. The ollgonucleotldes were studled ln parallel ln solutlon by vlbratlonal spectroscopy. A B->Z transltlon was detected by Raman spectroscopy cl.lrlng the crystalllzatlon procese for dCCACGTG>. Vlbratlonal spectroscopy shows that the dCGGCGCC> crystals adopt a B geametry. On the contrary the d<CCGCGG> sequence whlch ls shown to be able to undergo ln solutlon or ln fllms qulte easlly the B->Z transltlon, remalns trapped ln crystals ln a geametry whlch may correspond to an lntermedlate conformatlon often proposed ln modele of the B->Z transltlon. The crystals used ln thls study were characterlzed by X-ray dlffractlon. The unlt cell and space group have been determlned.
Cita: Urpi, L., Ridouxl, J.P., Liquier, J., Verdaguer, N., Fita. I., , Subirana, J.A.,...,Taillandier, E. (1989). Confonnations in crystals and solutions of d(CACGTG), d(CCGCGG) and d(GGCGCC) studied by vibrational spectroscopy. Nucleic Acids Research, 17 (16), 6669-6680.
Tamaño: 935.2Kb
Formato: PDF

URI: http://hdl.handle.net/11441/41403

DOI: 10.1093/nar/17.16.6669

Ver versión del editor

Mostrar el registro completo del ítem


Esta obra está bajo una Licencia Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 Internacional

Este registro aparece en las siguientes colecciones