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Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice

 

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Opened Access Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice
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Author: Bishop, Tammie
Gallagher, Denis
Pascual Bravo, Alberto
Lygate, Craig A.
Bono, Joseph P. de
Nicholls, Lynn G.
Ortega Sáenz, Patricia
Oster, Henrik
Wijeyekoon, Bhathiya
Sutherland, Andrew I.
Grosfeld, Alexandra
Aragones, Julian
Schneider, Martin
Geyte, Katie van
Teixeira, Dania
Diez Juan, Antonio
López Barneo, José
Channon, Keith M.
Maxwell, Patrick H.
Pugh, Christopher W.
Davies, Alun M.
Carmeliet, Peter
Ratcliffe, Peter J.
Department: Universidad de Sevilla. Departamento de Fisiología Médica y Biofísica
Date: 2008
Published in: Molecular and Cellular Biology, 28 (10), 3386-400.
Document type: Article
Abstract: Cell culture studies have implicated the oxygen-sensitive hypoxia-inducible factor (HIF) prolyl hydroxylase PHD3 in the regulation of neuronal apoptosis. To better understand this function in vivo, we have created PHD3_/_ mice and analyzed the neuro...
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URI: http://hdl.handle.net/11441/17802

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