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GDNF Is predominantly expressed in the PV+ neostriatal interneuronal ensemble in normal mouse and after Injury of the nigrostriatal pathway

 

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Opened Access GDNF Is predominantly expressed in the PV+ neostriatal interneuronal ensemble in normal mouse and after Injury of the nigrostriatal pathway
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Author: Hidalgo-Figueroa, María
Bonilla Jiménez, Sonia
Gutiérrez, Francisco
Pascual Bravo, Alberto
López Barneo, José
Department: Universidad de Sevilla. Departamento de Bioquímica Vegetal y Biología Molecular
Date: 2012
Published in: The Journal of Neuroscience, 32 (3), 864-872.
Document type: Article
Abstract: Glial cell line-derived neurotrophic factor (GDNF) is absolutely required for survival of dopaminergic (DA) nigrostriatal neurons and protect them from toxic insults. Hence, it is a promising, albeit experimental, therapy for Parkinson’s disease (PD...
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Format: PDF

URI: http://hdl.handle.net/11441/17471

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