Listar Instituto de Biomedicina de Sevilla (IBIS) por título
Mostrando ítems 67-86 de 196
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Falls predict acute hospitalization in Parkinson's disease
(IOS Press, 2023)Background: There is a need for identifying risk factors for hospitalization in Parkinson’s disease (PD) and also ...
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Feasibility of the implementation of LESS-CHRON in clinical practice: a pilot intervention study in older patients with multimorbidity
(Oxford Academic, 2023)Background and Objectives: Potentially inappropriate medication refers to the prescription of drugs whose risks outweigh ...
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FGFR1 Cooperates with EGFR in Lung Cancer Oncogenesis, and Their Combined Inhibition Shows Improved Efficacy
(Elsevier, 2019-04)Introduction: There is substantial evidence for the onco- genic effects of fi broblast growth factor receptor 1 ...
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First-in-human study of JNJ-63709178, a CD123/CD3 targeting antibody, in relapsed/refractory acute myeloid leukemia
(Wiley, 2022-12-23)This study aimed to identify a recommended phase II dose and evaluate the safety, tolerability, pharmacokinetics/pharmacodynamics, ...
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Four new loci associations discovered by pathway-based and network analyses of the genome-wide variability profile of Hirschsprung’s disease
(Springer Nature, 2012-12-28)Finding gene associations in rare diseases is frequently hampered by the reduced numbers of patients accessible. Conventional ...
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FUS (fused in sarcoma) is a component of the cellular response to topoisomerase I–induced DNA breakage and transcriptional stress
(Rockefeller University Press, 2019-02-26)FUS (fused in sarcoma) plays a key role in several steps of RNA metabolism, and dominant mutations in this protein are ...
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GBA Variants Influence Motor and Non-Motor Features of Parkinson’s Disease.
(Public Library Of Science, 2016-12-28)The presence of mutations in glucocerebrosidase (GBA) gene is a known factor increasing the risk of developing Parkinson’s ...
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GDNF Is predominantly expressed in the PV+ neostriatal interneuronal ensemble in normal mouse and after Injury of the nigrostriatal pathway
(2012)Glial cell line-derived neurotrophic factor (GDNF) is absolutely required for survival of dopaminergic (DA) nigrostriatal ...
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Genetic and cellular sensitivity of Caenorhabditis elegans to the chemotherapeutic agent cisplatin
(Company of Biologists Limited, 2018-06-21)Cisplatin and derivatives are commonly used as chemotherapeutic agents. Although the cytotoxic action of cisplatin on ...
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Genetic factors influencing frontostriatal dysfunction and the development of dementia in Parkinson's disease
(Public Library of Science, 2017)The dual syndrome hypothesis for cognitive impairment in Parkinson's disease (PD) establishes a dichotomy between a ...
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Genomic Evolution of Two Acinetobacter baumannii Clinical Strains from ST-2 Clones Isolated in 2000 and 2010 (ST-2_clon_2000 and ST-2_clon_2010)
(2016)Acinetobacter baumannii is a successful nosocomial pathogen due to its ability to persist in hospital environments by ...
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Glucose sensing by carotid body glomus cells: potential implications in disease
(Frontiers Media, 2014-10-15)The carotid body (CB) is a key chemoreceptor organ in which glomus cells sense changes in blood O2, CO2, and pH levels. ...
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Hematological Neoplasms with Eosinophilia
(MDPI, 2024-01-12)The diagnostic assessment of eosinophilias is complex, requiring a multidisciplinary approach and often involving diagnostic ...
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Heteroleptic (S^C)-cyclometallated gold(III) complexes as novel antiviral agents
(Elsevier, 2024-03)Despite the increasingly widespread clinical impact of adenovirus (HAdV) infections in healthy individuals and the ...
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HIF-2a is essential for carotid body development and function
(eLife Sciences Publications, 2018-04-19)Mammalian adaptation to oxygen flux occurs at many levels, from shifts in cellular metabolism to physiological adaptations ...
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High gamma activity distinguishes frontal cognitive control regions from adjacent cortical networks
(Elsevier, 2023)Though the lateral frontal cortex is broadly implicated in cognitive control, functional MRI (fMRI) studies suggest ...
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High levels of histones promote whole-genome-duplications and trigger a Swe1WEE1-dependent phosphorylation of Cdc28CDK1
(eLife Sciences, 2018-03-27)Whole-genome duplications (WGDs) have played a central role in the evolution of genomes and constitute an important source ...
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HIV-Infected Subjects With Poor CD4 T-Cell Recovery Despite Effective Therapy Express High Levels of OX40 and α4β7 on CD4 T-Cells Prior Therapy Initiation
(International Union of Immunological Societies, 2018-07-18)Background HIV-infected subjects with suboptimal CD4 restoration despite suppressive combined antiretroviral treatment ...
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HMGA2 overexpression predicts relapse susceptibility of blastemal Wilms tumor patients
(Impact Journals, 2017)Wilms tumor (WT) is an embryonal malignant neoplasm of the kidney that accounts for 6–7% of all childhood cancers. WT ...
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Hypertrophic Cardiomyopathy due to Mitochondrial Disease: Prenatal Diagnosis, Management, and Outcome
(Hindawi, 2012)A case of prenatally diagnosed fetal hypertrophic cardiomyopathy is reported. The mother was referred to our department ...