Buscar
Mostrando ítems 1-2 de 2
Artículo
Multiple signaling kinases target Mrc1 to prevent genomic instability triggered by transcription-replication conflicts
(Nature Publishing Group:, 2018)
Conflicts between replication and transcription machineries represent a major source of genomic instability and cells have evolved strategies to prevent such conflicts. However, little is known regarding how cells cope ...
Artículo
Nucleus-translocated mitochondrial cytochrome c liberates nucleophosmin-sequestered ARF tumor suppressor by changing nucleolar liquid-liquid phase separation.
(Nature Research, 2022-10-11)
The regular functioning of the nucleolus and nucleus-mitochondria crosstalk are considered unrelated processes, yet cytochrome c (Cc) migrates to the nucleus and even the nucleolus under stress conditions. Nucleolar ...