- idUS
- Investigación
- Ciencias de la Salud
- Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER)
- Listar Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER) por autor
Listar Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER) por autor "Huertas Sánchez, Pablo"
Mostrando ítems 1-8 de 8
-
Artículo
BRCA1 Accelerates CtIP-Mediated DNA-End Resection
Cruz García, Andrés; López Saavedra, Ana; Huertas Sánchez, Pablo (Elsevier, 2014)DNA-end resection is a highly regulated and critical step in the response and repair of DNA double-strand breaks. In ...
-
Artículo
CDK targets Sae2 to control DNA-end resection and homologous recombination
Huertas Sánchez, Pablo; Cortés Ledesma, Felipe; Sartori, Alessandro A.; Aguilera López, Andrés; Jackson, Stephen P. (Nature Publishing Group, 2008)DNA double-strand breaks (DSBs) are repaired by two principal mechanisms: non-homologous end-joining (NHEJ) and homologous ...
-
Artículo
Competing roles of DNA end resection and non-homologous end joining functions in the repair of replication-born double-strand breaks by sister-chromatid recombination
Muñoz Galván, Sandra; López Saavedra, Ana; Jackson, Stephen P.; Huertas Sánchez, Pablo; Cortés Ledesma, Felipe; Aguilera López, Andrés (Oxford University Press, 2013)While regulating the choice between homologous recombination and non-homologous end joining (NHEJ) as mechanisms of ...
-
Artículo
CtIP-mediated Alternative mRNA Splicing Fine-tunes the DNA Damage Response
Prados Carvajal, Rosario; Rodríguez Real, Guillermo; Gutiérrez Pozo, Gabriel; Huertas Sánchez, Pablo (Cold Spring Harbor Laboratory Press, 2021)In order to survive to the exposure of DNA damaging agents, cells activate a complex response that coordinates the cellular ...
-
Artículo
New tools to study DNA double-strand break repair pathway choice
Gómez Cabello, Daniel; Jimeno González, Sonia; Fernández Ávila, María Jesús; Huertas Sánchez, Pablo (2013) -
Artículo
Nuclear poly(A)-binding protein 1 is an ATM target and essential for DNA double-strand break repair
Prados Carvajal, Rosario; Huertas Sánchez, Pablo; Gavish Izakson, Michal; Bhavana Velpula, Bhagya; Elkon, Ran (Oxford University Press, 2018)The DNA damage response (DDR) is an extensive signaling network that is robustly mobilized by DNA double-strand breaks ...
-
Artículo
PHF2 regulates homology-directed DNA repair by controlling the resection of DNA double strand breaks
Alonso de la Vega, Ignacio; Paz Cabrera, María Cristina; Rother, Magdalena B; Wiegant, Wouter W; Checa Rodríguez, Cintia; Hernández Fernaud, Juan Ramón; Huertas Sánchez, Pablo; Freire, Raimundo; Attikum, Haico van; Smits, Veronique A J (Oxford University Press, 2020)Post-translational histone modifications and chromatin remodelling play a critical role controlling the integrity of the ...
-
Artículo
Targeting the centriolar replication factor STIL synergizes with DNA damaging agents for treatment of ovarian cancer
Rabinowicz, Noa; Mangala, Lingegowda S.; Brown, Kevin R.; Checa Rodríguez, Cintia; Castiel, Asher; Huertas Sánchez, Pablo (Impact Journals, 2017)Advanced ovarian cancer is an incurable disease. Thus, novel therapies are required. We wished to identify new therapeutic ...