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- Listar Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER) por autor
Listar Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER) por autor "Hmadcha, Abdelkrim"
Mostrando ítems 1-14 de 14
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Derivation of HVR1, HVR2 and HVR3 human embryonic stem cell lines from IVF embryos after preimplantation genetic diagnosis (PGD) for monogenic disorder
Hmadcha, Abdelkrim; Aguilera, Yolanda; Lozano Arana, María Dolores; Mellado, Nuria; Sánchez, Javier; Moya, Cristina; Sánchez Palazón, Luis; Palacios Calvo, José; Antiñolo Gil, Guillermo; Soria Escoms, Bernat (Elsevier, 2016)From 106 human blastocyts donate for research after in vitro fertilization (IVF) and preimplantation genetic diagnosis (PGD) ...
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EGF-induced adipose tissue mesothelial cells undergo functional vascular smooth muscle differentiation
Lachaud, Christian; López Beas, Javier; Soria Escoms, Bernat; Hmadcha, Abdelkrim (Nature Publishing Group, 2014)Recent studies suggested that the post-natal mesothelium retain differentiative potential of the embryonic mesothelium, ...
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Human Mesenchymal Stem Cells Prevent Neurological Complications of Radiotherapy
Soria Escoms, Bernat; Martín Montalvo, Alejandro; Aguilera García, Yolanda; Mellado, Nuria; López Beas, Javier; Herrera-Herrera, Isabel; López, Escarlata; Barcia, Juan A.; Álvarez Dolado, Manuel; Hmadcha, Abdelkrim; Capilla González, Vivian (Frontiers Media S.A., 2019-05-16)Radiotherapy is a highly effective tool for the treatment of brain cancer. However, radiation also causes detrimental ...
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Impact of transient down-regulation of DREAM in human embryonic stem cell pluripotency: The role of DREAM in the maintenance of hESCs
Fontán Lozano, Ángela del Carmen; Capilla González, Vivian; Aguilera, Yolanda; Mellado, Nuria; Carrión Rodríguez, Ángel Manuel; Soria Escoms, Bernat; Hmadcha, Abdelkrim (Elsevier, 2016)Little is knownabout the functions of downstreamregulatory element antagonist modulator (DREAM) inembryonic stem cells ...
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Low concentrations of nitric oxide delay the differentiation of embryonic stem cells and promote their survival
Martín, F.; Tejedo Huamán, Juan Rigoberto; Tapia Limonchi, R.; Mora Castilla, S.; Hmadcha, Abdelkrim; Soria Escoms, Bernat; Bedoya Bergua, Francisco Javier; Cahuana Macedo, Gladys Margot (2010) -
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LRH-1 agonism favours an immune-islet dialogue which protects against diabetes mellitus
Cobo Vuilleumier, Nadia; Lorenzo, Petra I.; García Rodríguez, Noelia; Herrera Gómez, Irene G.; Fuente Martín, Esther; López Noriega, Livia; Mellado Gil, José Manuel; Romero Zerbo, Silvana Y.; Lachaud, Christian; Hmadcha, Abdelkrim; Sánchez Palazón, Luis; Martín Montalvo, Alejandro; Soria Escoms, Bernat; Gauthier, Benoit R. (Nature Publishing Group, 2018-04-16)Type 1 diabetes mellitus (T1DM) is due to the selective destruction of islet beta cells by immune cells. Current therapies ...
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miR-7 Modulates hESC Differentiation into Insulin-Producing Beta-like Cells and Contributes to Cell Maturation
López Beas, Javier; Capilla González, Vivian; Aguilera, Yolanda; Mellado, Nuria; Lachaud, Christian; Martín, Franz; Smani Hajami, Tarik; Soria Escoms, Bernat; Hmadcha, Abdelkrim (The American Society of Gene and Cell Therapy, 2018-09-07)Human pluripotent stem cells retain the extraordinary capacity to differentiate into pancreatic beta cells. For this ...
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Oestrogen receptor β mediates the actions of bisphenol-A on ion channel expression in mouse pancreatic beta cells
Martínez-Pinna, Juan; Marroquí, Laura; Hmadcha, Abdelkrim; López Beas, Javier; Soriano, Sergi; Villar-Pazos, Sabrina; Alonso-Magdalena, Paloma; Santos, Reinaldo; Quesada, Iván; Martin, Franz; Soria Escoms, Bernat (Springer Nature, 2019-09)Aims/hypothesis: Bisphenol-A (BPA) is a widespread endocrine-disrupting chemical that has been associated with type 2 ...
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Resveratrol Ameliorates the Maturation Process of β-Cell-Like Cells Obtained from an Optimized Differentiation Protocol of Human Embryonic Stem Cells
Pezzolla, Daniela; López Beas, Javier; Lachaud, Christian; Domínguez Rodríguez, Alejandro; Smani Hajami, Tarik; Hmadcha, Abdelkrim (Public Library of Science, 2015)Human embryonic stem cells (hESCs) retain the extraordinary capacity to differentiate into different cell types of an adult ...
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The type 2 diabetes-associated HMG20A gene is mandatory for islet beta cell functional maturity article
Mellado Gil, José Manuel; Fuente Martín, Esther; Lorenzo Ovejero, Petra Isabel; Cobo Vuilleumier, Nadia; López Noriega, Livia; Martín Montalvo, Alejandro; Gracia Herrera Gómez, Irene de; Ceballos Chávez, María; Romero Zerbo, Silvana Y.; Hmadcha, Abdelkrim; Soria Escoms, Bernat; Bermúdez Silva, Francisco Javier; Reyes, José C.; Gauthier, Benoit R. (Springer Nature [academic journals on nature.com, 2018)HMG20A (also known as iBRAF) is a chromatin factor involved in neuronal differentiation and maturation. Recently small ...
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Therapeutic Potential of Mesenchymal Stem Cells for Cancer Therapy
Hmadcha, Abdelkrim; Martín Montalvo, Alejandro; Gauthier, Benoit R.; Soria Escoms, Bernat; Capilla González, Vivian (Frontiers Media S.A., 2020)Mesenchymal stem cells (MSCs) are among the most frequently used cell type for regenerative medicine. A large number of ...
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TRP Channels: Current Perspectives in the Adverse Cardiac Remodeling
Falcón Boyano, Débora; Galeano-Otero, Isabel; Calderón Sánchez, Eva María; Toro Estévez, Raquel del; Martín Bórnez, Marta; Rosado, Juan Antonio; Hmadcha, Abdelkrim; Smani Hajami, Tarik (Frontiers Media, 2019)Calcium is an important second messenger required not only for the excitation-contraction coupling of the heart but also ...
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Urocortin-2 Prevents Dysregulation of Ca2+ Homeostasis and Improves Early Cardiac Remodeling After Ischemia and Reperfusion
Domínguez Rodríguez, Alejandro; Mayoral-González, Isabel; Ávila Medina, Javier; Sánchez de Rojas de Pedro, Eva; Calderón Sánchez, Eva María; Díaz Carrasco, Ignacio; Hmadcha, Abdelkrim; Castellano Orozco, Antonio Gonzalo; Ordóñez Fernández, Antonio; Smani Hajami, Tarik (Frontiers Research Foundation, 2018-07-03)Aims: Urocortin-2 (Ucn-2) is a potent cardioprotector against Ischemia and Reperfusion (I/R) injuries. However, little is ...
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Zn2+ chelation by serum albumin improves hexameric Zn2+ -insulin dissociation into monomers after exocytosis
Pertusa, José A. G.; León Quinto, Trinidad; Berná, Genoveva; Tejedo Huamán, Juan Rigoberto; Hmadcha, Abdelkrim; Bedoya Bergua, Francisco Javier; Martín, Franz; Soria Escoms, Bernat (Public Library of Science, 2017)β-cells release hexameric Zn2+-insulin into the extracellular space, but monomeric Zn2+-free insulin appears to be the ...