Listar Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER) por título
Mostrando ítems 32-51 de 170
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Artículo
DDX47, MeCP2, and other functionally heterogeneous factors protect cells from harmful R loops
(Elsevier, 2023)Unscheduled R loops can be a source of genome instability, a hallmark of cancer cells. Although targeted proteomic ...
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Artículo
Depletion of the MFAP1/SPP381 Splicing Factor Causes R-Loop-Independent Genome Instability
(Elsevier, 2019)THO/TREX is a conserved complex with a role in messenger ribonucleoprotein biogenesis that links gene expression and genome ...
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Derivation of HVR1, HVR2 and HVR3 human embryonic stem cell lines from IVF embryos after preimplantation genetic diagnosis (PGD) for monogenic disorder
(Elsevier, 2016)From 106 human blastocyts donate for research after in vitro fertilization (IVF) and preimplantation genetic diagnosis (PGD) ...
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Capítulo de Libro
Detection of DNA-RNA hybrids in vivo
(Humana Press Inc., 2018)DNA-RNA hybrids form naturally during essential cellular functions such as transcription and replication. However, they ...
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Artículo
Differential expression of THOC1 and ALY mRNP biogenesis/export factors in human cancers
(2011)One key step in gene expression is the biogenesis of mRNA ribonucleoparticle complexes (mRNPs). Formation of the mRNP ...
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Artículo
Disease-Causing Mutations in BEST1 Gene Are Associated with Altered Sorting of Bestrophin-1 Protein
(MDPI, 2013)Mutations in BEST1 gene, encoding the bestrophin-1 (Best1) protein are associated with macular dystrophies. Best1 is ...
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Artículo
Distinct responses of human peripheral blood cells to different misfolded protein oligomers
(Wiley-Blackwell, 2021)Increasing evidence indicates that peripheral immune cells play a prominent role in neurodegeneration connected to protein ...
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Artículo
Distinct Roles of Mus81, Yen1, Slx1-Slx4, and Rad1 Nucleases in the Repair of Replication-Born Double-Strand Breaks by Sister Chromatid Exchange
(2012)Most spontaneous DNA double-strand breaks (DSBs) arise during replication and are repaired by homologous recombination ...
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Artículo
Dna-rna hybrids at dsbs interfere with repair by homologous recombination
(eLife Sciences Publications, 2021)DNA double-strand breaks (DSBs) are the most harmful DNA lesions and their repair is crucial for cell viability and genome ...
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Artículo
DNA-RNA hybrids: The risks of DNA breakage during transcription
(Springer Nature, 2017)Although R loops can occur at different genomic locations, the factors that determine their formation and frequency remain ...
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Artículo
Does tyrosyl DNA phosphodiesterase-2 play a role in hepatitis B virus genome repair?
(Public Library of Science, 2015)Hepatitis B virus (HBV) replication and persistence are sustained by a nuclear episome, the covalently closed circular ...
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Artículo
Dysfunction of the unfolded protein response increases neurodegeneration in aged rat hippocampus following proteasome inhibition
(Wiley-Blackwell, 2009)Dysfunctions of the ubiquitin proteasome system (UPS) have been proposed to be involved in the aetiology and/or progression ...
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Artículo
Editorial: Molecular chaperones and neurodegeneration
(Frontiers Media, 2017) -
Artículo
EGF-induced adipose tissue mesothelial cells undergo functional vascular smooth muscle differentiation
(Nature Publishing Group, 2014)Recent studies suggested that the post-natal mesothelium retain differentiative potential of the embryonic mesothelium, ...
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Tesis Doctoral
Elongación transcripcional en Saccharomyces Cerevisiae influencia en el control del ciclo celular y nuevas herramientas para su estudio "in vivo"
(2007)La transcripción es el proceso mediante el cual la información genética, contenida en el DNA, es expresada en forma de ...
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Artículo
Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability
(Elsevier, 2019)Although correlations between RNA polymerase II (RNAPII) transcription stress, R-loops, and genome instability have been ...
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Artículo
Endogenous topoisomerase II-mediated DNA breaks drive thymic cancer predisposition linked to ATM deficiency
(Springer Nature, 2020)The ATM kinase is a master regulator of the DNA damage response to double-strand breaks (DSBs) and a well-established ...
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Artículo
Epigenetic features of human telomeres
(Oxford University Press, 2018)Although subtelomeric regions in humans are heterochromatic, the epigenetic nature of human telomeres remains controversial. ...
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Artículo
Expression of TDRD9 in a subset of lung carcinomas by CpG island hypomethylation protects from DNA damage
(Impact Journals, 2018)Tudor domain containing protein 9 (TDRD9) is a RNA helicase normally expressed in the germline, where it is involved in ...
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Artículo
FANCD2 facilitates replication through common fragile sites
(Elsevier, 2016)Common fragile sites (CFSs) are genomic regions that are unstable under conditions of replicative stress. Although the ...