Química Orgánica y Farmacéutica
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Artículo
Design and manufacturing by fused filament technique of novel YSZ porous grafts infiltrated with PCL/PVA/AgNPs for large bone defects repairing
(Elsevier, 2024-02-19)Addressing large bone segmental defects remains a profound challenge in orthopaedic surgery, demanding graft designs that ...
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Patente. Invención
Compuestos derivados de sulforafano, método de obtención y su uso médico, alimenticio y cosmético
(Oficina Española de Patentes y Marcas (OEPM)., 2014)Compuestos derivados de sulforafano, método de obtención y su uso médico, alimenticio y cosméticoLa presente invención ...
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Biodegradable double cross-linked chitosan hydrogels for drug delivery: Impact of chemistry on rheological and pharmacological performance
(Elsevier, 2020-12)This study investigates the impact of dual ionic and covalent cross-links (ion-XrL and cov-XrL) on the properties of ...
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Metabolites and tissue distribution of resveratrol in the pig
(Wiley-Blackwell, 2011-08)Scope: trans-Resveratrol (RES) and/(or) its metabolites exert many effects in vivo. Our aim was to study the metabolism ...
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Chiral sulfur derivatives in the allylation of acyl hydrazones: C 2-symmetric bis-sulfinamides as enhanced chiral organic promoters
(Royal Society of Chemistry, 2010-10)Monosulfinamides and C2-symmetric bis-sulfinamides are convenient neutral chiral promoters in the allylation of acyl ...
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DMAP-Catalysed Sulfinylation of Diacetone-D-Glucose: Improved Method for the Synthesis of Enantiopure tert-Butyl Sulfoxides and tert-Butanesulfinamide
(Wiley Online Library, 2014-11)An improved method for the tert-butanesulfinylation of diacetone glucose with tert-butanesulfinyl chloride is reported. ...
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An Efficient and Practical Method for the Enantioselective Synthesis of Tertiary Trifluoromethyl Carbinols
(Wiley Online Library, 2018-03)An efficient sulfinamide/olefin based chiral ligand, MetSulfolefin, has been developed for the enantioselective rhodium-catalysed ...
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Sulfinamide Phosphinates as Chiral Catalysts for the Enantioselective Organocatalytic Reduction of Imines
(American Chemical Society, 2016-07)A new type of chiral sulfinamide phosphinate catalysts with up to three stereogenic centers, readily accessible from ...
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Preventive oral treatment with resveratrol pro-prodrugs drastically reduce colon inflammation in rodents
(American Chemical Society, 2010-10-28)There is no pharmaceutical or definitive surgical cure for inflammatory bowel diseases (IBDs). The naturally occurring ...
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Tandem ATRP/Diels-Alder Synthesis of PolyHEMA-based Hydrogels
(Royal Society of Chemistry, 2014)The efficient, controlled polymerization of a batch of new poly(hydroxyethyl methacrylate-co-furfuryl methacrylate)s, ...
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Resveratrol and some glucosyl, glucosylacyl, and glucuronide derivatives reduce Escherichia coli O157:H7, Salmonella typhimurium, and Listeria monocytogenes Scott A adhesion to colonic epithelial cell lines
(American Chemical Society, 2012)The efficacy of resveratrol and some glucosyl, glucosylacyl, and glucuronide derivatives in inhibiting the adhesion of ...
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Identifying Coordination Geometries of Metal Aquaions in Water: Application to the Case of Lanthanoid and Actinoid Hydrates
(American Chemical Society, 2016)The angular distribution function (ADF) associated with the oxygen-metal ion-oxygen angle (OMO) of several trivalent ...
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Synthetic Polymers from Sugar-Based Monomers
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Artículo
Solving the Hydration Structure of the Heaviest Actinide Aqua IonKnown: The Californium(III) Case
(Wiley-Blackwell, 2010)Wish they all could be californium: X-ray absorption spectroscopy (black points) and Monte Carlo simulations (blue line) ...
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The Gut Microbiota Ellagic Acid-Derived Metabolite Urolithin A and Its Sulfate Conjugate Are Substrates for the Drug Efflux Transporter Breast Cancer Resistance Protein (ABCG2/BCRP)
(American Chemical Society, 2013)The breast cancer resistance protein (BCRP/ABCG2) is a drug efflux transporter that can affect the pharmacological and ...
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Neuroprotective and Anti-inflammatory Effects of Pterostilbene Metabolites in Human Neuroblastoma SH-SY5Y and RAW 264.7 Macrophage Cells
(American Chemical Society, 2020)Oxidative stress is known to be a key factor in many neurodegenerative diseases. Inflammation also plays a relevant role ...
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Surface-Active Properties of Lipophilic AntioxidantsTyrosol and Hydroxytyrosol Fatty Acid Esters: A PotentialExplanation for the Nonlinear Hypothesis of the AntioxidantActivity in Oil-in-Water Emulsions
(American Chemical Society, 2001)Our group has recently observed a nonlinear tendency in antioxidant capacity of different hydroxytyrosol fatty acid esters ...
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Highly Polar Carbohydrates Stack Onto DNA Duplexes Via CH/π Interactions
(American Chemical Society, 2011)Carbohydrate-nucleic acid contacts are known to be a fundamental part of some drug-DNA recognition processes. Most of these ...
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(R)-8-Methylsulfinyloctyl isothiocyanate from Nasturtium officinale inhibits LPS-induced immunoinflammatory responses in mouse peritoneal macrophages: chemical synthesis and molecular signaling pathways involved
(Royal Society of Chemistry, 2023-07-20)The aim of this study was to develop an optimal synthetic route to obtain natural (R)-8-methylsulfinyloctyl isothiocyanate ...