Artículos (Farmacología)
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Artículo
Abrupt Photoperiod Changes Differentially Modulate Hepatic Antioxidant Response in Healthy and Obese Rats: Effects of Grape Seed Proanthocyanidin Extract (GSPE)
(MDPI, 2023-12-02)Disruptions of the light/dark cycle and unhealthy diets can promote misalignment of biological rhythms and metabolic ...
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Performance of a Point-of-Care Test for Infliximab Levels in Patients with Inflammatory Bowel Disease: A Comparison to ELISA
(Springer, 2023-11-09)Background Therapeutic drug monitoring of infliximab levels in patients with inflammatory bowel disease (IBD) optimizes ...
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Isolation and structural determination of cis- and trans-p-coumaroyl-secologanoside (comselogoside) from olive oil waste (alperujo). Photoisomerization with ultraviolet irradiation and antioxidant activities
(Elsevier, 2024-01-30)p-Coumaroyl-6́-secologanoside (comselogoside) is a secoiridoid identified in large amounts in olive fruits, although no ...
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Evaluation of temocillin efficacy against KPC-2-producing Klebsiella pneumoniae isolates in a hollow-fibre infection model
(Oxford University Press, 2024-02-09)Background: Temocillin is an old antimicrobial that is resistant to hydrolysis by ESBLs but has variable activity against ...
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FarmaEscape El Retorno: el empleo de una Escape Room como herramienta de aprendizaje en los estudios de la Facultad de Farmacia de la Universidad de Sevilla
(Real e Ilustre Colegio Oficial de Farmacéuticos, 2023)Una Escape Room es un juego de escapismo en el que un grupo de personas están “atrapadas” en una sala cerrada, debiendo ...
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Mechanisms of increased gastric protection after NSAID-administration in rats consuming virgin olive oil diets
(Elsevier, 2008)This study was aimed to know the immunomodulatory effects of defined extra virgin olive oil (EVOO) diets on indomethacin ...
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Photoprotective Effects of Two New Morin-Schiff Base Derivatives on UVB-Irradiated HaCaT Cells
(Multidisciplinary Digital Publishing Institute (MDPI), 2024-01)Ultraviolet (UV) radiation harms the skin, causing oxidative damage, inflammation, and disruption of the skin’s barrier ...
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Functional Features of the Exopolysaccharide Extracts Produced by Lactiplantibacillus Strains Isolated from Table Olives
(Royal Society of Chemistry, 2024)This study evaluates the functional characteristics of the exopolysaccharide (EPS) extracts produced by various strains ...
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Exploring Metabolic and Gut Microbiome Responses to Paraquat Administration in Male Wistar Rats: Implications for Oxidative Stress
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)In this study, we examined the metabolic and gut microbiome responses to paraquat (PQ) in male Wistar rats, focusing on ...
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An Efficient and Practical Method for the Enantioselective Synthesis of Tertiary Trifluoromethyl Carbinols
(Wiley Online Library, 2018-03)An efficient sulfinamide/olefin based chiral ligand, MetSulfolefin, has been developed for the enantioselective rhodium-catalysed ...
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(R)-8-Methylsulfinyloctyl isothiocyanate from Nasturtium officinale inhibits LPS-induced immunoinflammatory responses in mouse peritoneal macrophages: chemical synthesis and molecular signaling pathways involved
(Royal Society of Chemistry, 2023-07-20)The aim of this study was to develop an optimal synthetic route to obtain natural (R)-8-methylsulfinyloctyl isothiocyanate ...
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Characterization of bioactive compounds in defatted hempseed (Cannabis sativa L.) by UHPLC-HRMS/MS and anti-inflammatory activity in primary human monocytes
(Royal Society of Chemistry, 2020)Hempseed (Cannabis sativa L.) has beneficial impact on human health mainly because of its wide variability of bioactive ...
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Potential therapeutic applications of the genus Annona: Local and traditional uses and pharmacology
(Elsevier, 2018)Ethno-pharmacological relevance Annona species (Annonaceae) have long been used as traditional herbal medicines by native ...
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Design, synthesis and biological studies of a library of NK1-Receptor Ligands Based on a 5-arylthiosubstituted 2-amino-4,6-diaryl-3-cyano-4H-pyran core: Switch from antagonist to agonist effect by chemical modification
(Elsevier, 2017)A library of 5-arylthiosubstituted 2-amino-4,6-diaryl-3-cyano-4H-pyrans has been synthesized as a new family of non-peptide ...
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Screening for selective anticancer activity of plants from Grazalema Natural Park, Spain
(Taylor & Francis, 2019-12-02)Since plants are an important source of anticancer drugs, we have carried out a random screening for selective anticancer ...
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Dietary Manipulation of Amino Acids for Cancer Therapy
(MDPI, 2023)Cancer cells cannot proliferate and survive unless they obtain sufficient levels of the 20 proteinogenic amino acids (AAs). ...
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Repurposing Study of 4-Acyl-1-phenylaminocarbonyl-2-substituted-piperazine Derivatives as Potential Anticancer Agents-In Vitro Evaluation against Breast Cancer Cells
(MDPI, 2023)first_pagesettingsOrder Article Reprints Open AccessArticle Repurposing Study of 4-Acyl-1-phenylaminocarbonyl-2-substituted-piperazine ...
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Perfluorohexyloctane in dry eye disease: A systematic review of its efficacy and safety as a novel therapeutic agent
(Elsevier, 2023)Perfluorohexyloctane (F6H8), a physically and chemically inert synthetic compound, has recently emerged as a promising ...
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Potential interactions between pangenotypic direct-acting antivirals and concomitant cardiovascular therapies in patients with chronic hepatitis C virus infection
(SAGE Publications, 2020)To identify potential drug interactions (DIs) between pangenotypic direct-acting antivirals (pDAAs) and concomitant cardiovascular (CV) therapies in patients with chronic hepatitis C (CHC).
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Effects of Dietary Oleacein Treatment on Endothelial Dysfunction and Lupus Nephritis in Balb/C Pristane-Induced Mice
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)Systemic lupus erythematosus (SLE) is a chronic immune-inflammatory disease characterized by multiorgan affectation and ...