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Artículo
Multidrug resistance transporter profile reveals MDR3 as a marker for stratification of blastemal Wilms tumour patients
(Impact Journals, 2017)
Wilms tumour (WT) is the most common renal tumour in children. Most WT patients respond to chemotherapy, but subsets of tumours develop resistance to chemotherapeutic agents, which is a major obstacle in their successful ...
Tesis Doctoral
Gastritis crónica asociada a Helicobacter pylori en pacientes mayores de 65 años: Prevalencia, patogénesis y adhesión a las áreas de metaplasia intestinal.
(2000-06-29)
Durante las dos últimas décadas, a partir del descubrimiento del Helicobacter pylori, los estudios se han encaminado, en primer lugar, al conocimiento de sus características, y posteriormente, a la identificación de los ...
Tesis Doctoral
Artículo
Apoptotic microtubules delimit an active caspase free area in the cellular cortex during the execution phase of apoptosis
(NATURE PUBLISHING GROUP, 2013)
Apoptotic microtubule network (AMN) is organized during apoptosis, forming a cortical structure beneath plasma membrane, which has an important role in preserving cell morphology and plasma membrane permeability. The aim ...
Tesis Doctoral
Células enteroargentafines. Sus modificaciones en diversos estados patológicos y experimentales
(1964-07-30)
CONCLUSIONES 1. Utilizando los métodos de MASSON y de GROS se ha precedido a comprobar la presencia de células enteroargentafines en el tracto digestivo y órganos genitourinarios de distintas especies de vertebrados y del ...
Tesis Doctoral
Artículo
Hippo pathway effectors YAP1/TAZ induce an EWS-FLI1-opposing gene signature and associate with disease progression in Ewing sarcoma
(Wiley, 2020)
YAP1 and TAZ (WWTR1) oncoproteins are thefinal transducers of the Hippo tumor suppressor pathway. Deregula-tion of the pathway leads to YAP1/TAZ activation fostering tumorigenesis in multiple malignant tumor types, includ-ing ...
Artículo
Microstructural and strength changes in trabecular bone in elderly patients with type 2 diabetes mellitus
(MPDI, 2021-03-23)
Type 2 diabetes mellitus (T2DM) is one of the most common chronic diseases worldwide and it is associated with an increased risk of osteoporosis and fragility fractures. Our aim is to analyze the effect of T2DM on bone ...
Artículo
Granulomas en dermatopatología: principales entidades. Parte II
(Elsevier, 2021-04-21)
Esta es la segunda parte de una serie dedicada a la patología granulomatosa en la biopsia cutánea. Mientras que en la primera parte hablamos, entre otras, de algunas condiciones metabólicas y tumorales, esta segunda parte ...
Artículo
Molecular diagnosis in non-small-cell lung cancer: expert opinion on ALK and ROS1 testing
(BMJ Publishing Group, 2021)
The effectiveness of targeted therapies with tyrosine kinase inhibitors in non-small-cell lung cancer (NSCLC) depends on the accurate determination of the genomic status of the tumour. For this reason, molecular ...