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Artículo
Acute oxidant damage promoted on cancer cells by amitriptyline in comparison with some common chemotherapeutic drugs
(Wolters Kluwer Health, 2010)
Oxidative therapy is a relatively new anticancer strategy based on the induction of high levels of oxidative stress, achieved by increasing intracellular reactive oxygen species (ROS) and/or by depleting the ...
Tesis Doctoral
Estudio etiopatogénico del linfoepitelioma no endémico
(2011)
El carcinoma nasofaríngeo (CNF) es una neoplasia que tiene una alta incidencia en China y algunas áreas del sudeste asiático, con una asociación frecuente a la infección por el VEB, pero poco se conoce sobre su patogénesis ...
Artículo
Artículo
Amitriptyline down-regulates coenzyme Q10 biosynthesis in lung cancer cells
(Elsevier, 2017)
Amitriptyline, a tricyclic antidepressant, has been proposed as an antitumoral drug in oxidative therapy. Its pro-apoptotic effects, mediated by high reactive oxygen species generation, have been already described. In ...
Artículo
Apoptotic microtubules delimit an active caspase free area in the cellular cortex during the execution phase of apoptosis
(NATURE PUBLISHING GROUP, 2013)
Apoptotic microtubule network (AMN) is organized during apoptosis, forming a cortical structure beneath plasma membrane, which has an important role in preserving cell morphology and plasma membrane permeability. The aim ...
Tesis Doctoral
Tesis Doctoral
Aproximación al estudio biomolecular del carcinoma nasofaríngeo
(2010)
El carcinoma nasofaríngeo se presenta con baja incidencia en los países occidentales, siendo muy frecuente en países asiáticos donde se ha vinculado, en su patogénesis, con la infección endémica por el virus de Epstein-Barr. ...
Artículo
Fibroblasts Collagen Production and Histological Alterations in Hereditary Gingival Fibromatosis
(MDPI, 2019)
Hereditary gingival fibromatosis is a disorder for which the etiology remains unknown. We aimed to evaluate the fibroblasts and histological alterations to give new clues. A father and a daughter of a family showing gingival ...
Artículo
Coenzyme Q(10) Therapy
(KARGER, 2014)
For a number of years, coenzyme Q 10 (CoQ 10 ) was known for its key role in mitochondrial bioenergetics; later studies demonstrated its presence in other subcellular fractions and in blood plasma, and extensively ...
Tesis Doctoral
Nuevas terapias bioactivas preventivas y terapéuticas en un modelo animal de enfermedad de Crohn
(2019-12-20)
La enfermedad inflamatoria intestinal (EII), como la enfermedad de Crohn (EC) y la colitis ulcerosa (CU), son un trastorno inflamatorio crónico del tracto digestivo que cursa con fases agudas y de remisión. La etiología ...