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ListarArtículos (Bioquímica y Biología Molecular) por materia "Neurodegeneration"

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      APOE in the bullseye of neurodegenerative diseases: impact of the APOE genotype in Alzheimer’s disease pathology and brain diseases 

      Fernández Calle, R.; Konings, Sabine C.; Frontinan Rubio, Javier; Garcia Revilla, Juan; Camprubí Ferrer, Lluís; Svensson, Martina; Martinson, Isak; Boza Serrano, Antonio; Venero Recio, José Luis; Nielsen, Henrietta M.; Gouras, Gunnar K.; Deierborg, Tomas (Springer Nature, 2022)
      ApoE is the major lipid and cholesterol carrier in the CNS. There are three major human polymorphisms, apoE2, apoE3, and ...
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      Aβ oligomers trigger necroptosis-mediated neurodegeneration via microglia activation in Alzheimer’s disease 

      Salvadores, Natalia; Moreno González, Inés; Gámez, Nazaret; Quiroz, Gabriel; Vegas Gómez, Laura; Escandón, Marcela; Jiménez Muñoz, Sebastián; Vitorica Ferrández, Francisco Javier; Gutiérrez Pérez, Antonia; Soto, Claudio; Court, Felipe A. (BMC, 2022)
      Alzheimer’s disease (AD) is a major adult-onset neurodegenerative condition with no available treatment. Compelling reports ...
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      Cell Death Related Proteins Beyond Apoptosis in the CNS 

      Bahatyrevich Kharitonik, Bazhena; Medina Guzmán, Rafael; Flores Cortés, Alicia; García Cruzado, Marta; Kavanagh, Edel T.; Burguillos García, Miguel Ángel (Frontiers Media S.A., 2022)
      Cell death related (CDR) proteins are a diverse group of proteins whose original function was ascribed to apoptotic cell ...
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      Editorial: Neurodegeneration: From Genetics to Molecules (Part II) 

      Carvajal, karla Guadalupe; Martínez de Pablos, Rocío; Campos Peña, Victoria (Frontiers Media, 2021)
      Among non-transmissible chronic diseases, neurodegenerative complications have become a big challenge in public health. ...
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      Regional difference in inflammatory response to LPS-injection in the brain: Role of microglia cell density 

      Pintado Losa, Cristina; Revilla Torres, María Elisa; Vizuete Chacón, María Luisa; García Cuervo, Luisa; Vitorica Ferrández, Francisco Javier; Ruano Caballero, Diego; Castaño Navarro, Angélica (Elsevier, 2011)
      To elucidate whether density of cells could contribute to the extent of microglial activation, we performed in vitro assays ...
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      Synaptic defects in spinal muscular atrophy animal models 

      Torres-Benito, Laura; Ruiz Laza, Rocío; Tabares, Lucía (Wiley, 2011)
      Proximal spinal muscular atrophy, the most frequent genetic cause of childhood lethality, is caused by homozygous loss ...
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      The HERC proteins and the nervous system 

      Pérez Villegas, Eva María; Ruiz Laza, Rocío; Bachiller, Sara; Ventura, Francesc; Armengol, Jose A.; Rosa, Jose Luis (Elsevier, 2021)
      The HERC protein family is one of three subfamilies of Homologous to E6AP C-terminus (HECT) E3 ubiquitin ligases. Six HERC ...
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      Transgenic Mouse Models of Alzheimer’s Disease: An Integrative Analysis 

      Sánchez Varo, Raquel María; Mejías Ortega, Marina; Fernández Valenzuela, Juan José; Núñez Díaz, Cristina; Cáceres Palomo, Laura; Vegas Gómez, Laura; Sánchez Mejías, Elisabeth; Trujillo Estrada, Laura Isabel; García León, Juan Antonio; Moreno González, Inés; Vizuete Chacón, María Luisa; Vitorica Ferrández, Francisco Javier; Baglietto Vargas, David; Gutiérrez Pérez, Antonia (Multidisciplinary Digital Publishing Institute (MDPI), 2022)
      Alzheimer’s disease (AD) constitutes the most prominent form of dementia among elderly individuals worldwide. Disease ...