ListarArtículos (Bioquímica y Biología Molecular) por materia "Microglia"
Mostrando ítems 1-17 de 17
-
Artículo
Aβ oligomers trigger necroptosis-mediated neurodegeneration via microglia activation in Alzheimer’s disease
(BMC, 2022)Alzheimer’s disease (AD) is a major adult-onset neurodegenerative condition with no available treatment. Compelling reports ...
-
Artículo
Chronic stress enhances microglia activation and exacerbates death of nigral dopaminergic neurons under conditions of inflammation
(BioMed Central, 2014)Background: Parkinson’s disease is an irreversible neurodegenerative disease linked to progressive movement disorders and ...
-
Artículo
Cyclic multiplex fluorescent immunohistochemistry and machine learning reveal distinct states of astrocytes and microglia in normal aging and Alzheimer’s disease
(BMC, 2022)Background Astrocytes and microglia react to Aβ plaques, neurofibrillary tangles, and neurodegeneration in the Alzheimer’s ...
-
Artículo
Distinct Microglial Responses in Two Transgenic Murine Models of TAU Pathology
(Frontiers Media Research Foundation, 2018-11-14)Microglial cells are crucial players in the pathological process of neurodegenerative diseases, such as Alzheimer’s disease ...
-
Artículo
Galectin-3 Deletion Reduces LPS and Acute Colitis-Induced Pro-Inflammatory Microglial Activation in the Ventral Mesencephalon
(Frontiers Media, 2021)Parkinson’s disease is a highly prevalent neurological disorder for which there is currently no cure. Therefore, the ...
-
Artículo
Galectin‑3, a novel endogenous TREM2 ligand, detrimentally regulates infammatory response in Alzheimer’s disease
(Springer, 2019)Alzheimer’s disease (AD) is a progressive neurodegenerative disease in which the formation of extracellular aggregates of ...
-
Artículo
Human Pluripotent Stem Cell-Derived Neural Cellsas a Relevant Platform for Drug Screening inAlzheimer’s Disease
(MDPI, 2020)Extracellular amyloid-beta deposition and intraneuronal Tau-laden neurofibrillary tanglesare prime features of Alzheimer’s ...
-
Artículo
Inflammatory Animal Models of Parkinson's Disease
(IOS Press, 2022)Accumulating evidence suggests that microglia and peripheral immune cells may play determinant roles in the pathogenesis ...
-
Artículo
LPS priming before plaque deposition impedes microglial activation and restrains Abeta pathology in the 5xFAD mouse model of Alzheimer's disease.
(Elsevier, 2023-10)Microglia have an innate immunity memory (IIM) with divergent functions in different animal models of neurodegenerative ...
-
Artículo
Microglia: Agents of the CNS Pro-Inflammatory Response
(Multidisciplinary Digital Publishing Institute (MDPI), 2020)The pro-inflammatory immune response driven by microglia is a key contributor to the pathogenesis of several neurodegenerative ...
-
Artículo
Microglial Caspase-3 is essential for modulating hippocampal neurogenesis.
(Elsevier, 2023)Adult hippocampal neurogenesis (AHN) is a process involved in numerous neurodegenerative diseases. Many researchers have ...
-
Artículo
Monocyte-derived Cells Invade Brain Parenchyma and Amyloid Plaques in Human Alzheimer’s Disease Hippocampus
(Springer Nature, 2023)Microglia are brain-resident myeloid cells and play a major role in the innate immune responses of the CNS and the ...
-
Artículo
Should we open fire on microglia? Depletion models as tools to elucidate microglial role in health and alzheimer’s disease
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)Microglia play a critical role in both homeostasis and disease, displaying a wide variety in terms of density, functional ...
-
Artículo
Spatio-temporal activation of caspase-8 in myeloid cells upon ischemic stroke
(BioMed Central, 2016)Ischemic stroke (caused by thrombosis, embolism or vasoconstriction) lead to the recruitment and activation of immune cells ...
-
Artículo
The human bone marrow harbors a CD45− CD11B+ cell progenitor permitting rapid microglia-like cell derivative approaches
(Wiley-Blackwell, 2021)Microglia, the immune sentinel of the central nervous system (CNS), are generated from yolk sac erythromyeloid progenitors ...
-
Artículo
The role of Galectin-3 in α-synuclein-induced microglial activation
(BioMed Central, 2014)Background: Parkinson ’ s disease (PD) is the most prevalent neurodegenerative motor disorder. The neuropathology ...
-
Artículo
Transgenic Mouse Models of Alzheimer’s Disease: An Integrative Analysis
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)Alzheimer’s disease (AD) constitutes the most prominent form of dementia among elderly individuals worldwide. Disease ...