Buscar
Mostrando ítems 1-10 de 12
Artículo
Role of leptin in non-alcoholic fatty liver disease
(MDPI, 2021-06-30)
Non-alcoholic fatty liver disease (NAFLD), which affects about a quarter of the global population, poses a substantial health and economic burden in all countries, yet there is no approved pharmacotherapy to treat this ...
Artículo
Cancer nano-immunotherapy: the novel and promising weapon to fight cancer
(Mdpi Ag, 2024)
Cancer is a complex disease that, despite advances in treatment and the greater understanding of the tumor biology until today, continues to be a prevalent and lethal disease. Chemotherapy, radiotherapy, and surgery are ...
Artículo
Tissue-specific activated regulatory lymphocytes immunophenotype in chronic rhinosinusitis with nasal polyps
(EDICIONES DOYMA S A, 2023)
Artículo
Obesity as a Risk Factor for Dementia and Alzheimer’s Disease: The Role of Leptin
(MDPI AG, 2022)
Obesity is a growing worldwide health problem, affecting many people due to excessive saturated fat consumption, lack of exercise, or a sedentary lifestyle. Leptin is an adipokine secreted by adipose tissue that increases ...
Artículo
Dendritic cells as a therapeutic strategy in acute myeloid leukemia: vaccines
(MDPI, 2024-02)
Dendritic cells (DCs) serve as professional antigen-presenting cells (APC) bridging innate and adaptive immunity, playing an essential role in triggering specific cellular and humoral responses against tumor and infectious ...
Artículo
Nutraceuticals as potential therapeutic modulators in immunometabolism
(MDPI, 2023-01-13)
Nutraceuticals act as cellular and functional modulators, contributing to the homeostasis of physiological processes. In an inflammatory microenvironment, these functional foods can interact with the immune system by ...
Artículo
Modulation of Beta-Amyloid-Activated Primary Human Neutrophils by Dietary Phenols from Virgin Olive Oil
(MDPI, 2023)
The defense mechanism against harmful stimuli is inflammation. Indeed, neurodegenerative disorders can arise as a result of a persistent neuroinflammation. Beta-amyloid (Aβ1-42) is an early trigger in the origination of ...
Artículo
Dendritic cells: the yin and yang in disease progression
(Frontiers Media, 2024-01-04)
Dendritic cells (DCs) are antigen presenting cells that link innate and adaptive immunity. DCs have been historically considered as the most effective and potent cell population to capture, process and present antigens to ...
Tesis Doctoral
Modulación de lxrα por polifenoles y ácido oleico mediada por proteínas quinasas en células fagocíticas humanas
(2015-05-29)
Los receptores nucleares LXR (Liver X receptors) están implicados en la regulación de numerosos procesos fisiológicos, fundamentalmente la homeostasis del colesterol y ácidos grasos, y la expresión de genes implicados en ...
Artículo
Sulforaphane reduces the chronic inflammatory immune response of human dendritic cells
(MDPI, 2023)
Background: Sulforaphane (SFN) is an isothiocyanate of vegetable origin with potent antioxidant and immunomodulatory properties. The characterization of its pleiotropic activity in human dendritic cells (DCs) is poorly ...