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Artículo
Artículo
Methylation-dependent gene silencing induced by interleukin 1β via nitric oxide production
(Rockefeller University Press, 1999-12-06)
Interleukin (IL)-1 b is a pleiotropic cytokine implicated in a variety of activities, including damage of insulin-producing cells, brain injury, or neuromodulatory responses. Many of these effects are mediated by nitric ...
Tesis Doctoral
Epigenética de los procesos de autorrenovación, pluripotencialidad y diferenciación de las células troncales
(2010)
El objetivo general de esta tesis ha sido definir la importancia que poseen los procesos epigenéticos sobre el mantenimiento del estado pluripotente y el proceso de diferenciación de las células troncales embrionarias. ...
Tesis Doctoral
Artículo
Preconditioning of Microglia by α-Synuclein Strongly Affects the Response Induced by Toll-like Receptor (TLR) Stimulation
(PLOS, 2013)
In recent years, it has become accepted that α-synuclein (αSyn) has a key role in the microglia-mediated neuroinflammation, which accompanies the development of Parkinson's disease and other related disorders, such as ...