- idUS
- Investigación
- Ciencias de la Salud
- Bioquímica Médica y Biología Molecular e Inmunología
- Listar Bioquímica Médica y Biología Molecular e Inmunología por autor
Listar Bioquímica Médica y Biología Molecular e Inmunología por autor "Roodveldt, Cintia"
Mostrando ítems 1-9 de 9
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Tesis Doctoral
Alpha-synuclein and immune system crosstalk in parkinson's disease; therapeutic approaches of its modulation by molecular chaperones
Labrador Garrido, Adahir (2017-05-22)This Doctoral Thesis is focused on the interplay between the immune system and the Parkinson’s related protein alpha-Synuclein. ...
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Artículo
Commentary: Immunochemical Markers of the Amyloid Cascade in the Hippocampus in Motor Neuron Diseases
Johnson, Ian Paul; Roodveldt, Cintia (Frontiers Media, 2017)In case we needed reminding, age-related neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease ...
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Artículo
Differential Interactome and Innate Immune Response Activation of Two Structurally Distinct Misfolded Protein Oligomers
Mannini, Benedetta; Vecchi, Giulia; Labrador Garrido, Adahir; Fabre, Bertrand; Pozo Pérez, David; Dobson, Christopher M.; Roodveldt, Cintia (American Chemical Society, 2019)The formation of misfolded protein oligomers during early stages of amyloid aggregation and the activation of neuroinflammatory ...
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Tesis Doctoral
Esclerosis lateral amiotrófica: investigaciones en el modelo sod1g93a y correlaciones de interés clínico
Cejudo Guillén, Marta (2016-06-03)La esclerosis lateral amiotrófica (ELA) es una enfermedad neurodegenerativa, incurable y de carácter fatal en un plazo de ...
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Artículo
Glial innate immunity generated by non-aggregated alpha-synuclein in mouse: differences between wild-type and Parkinson's disease-linked mutants
Roodveldt, Cintia; Labrador Garrido, Adahir; Gonzalez-Rey, Elena; Fernández Montesinos, Rafael; Caro, Marta; Lachaud, Christian; Waudby, Christopher A.; Delgado, Mario; Dobson, Christopher M.; Pozo Pérez, David (Public Library Science, 2010) -
Artículo
Immunization with α-synuclein/Grp94 reshapes peripheral immunity and suppresses microgliosis in a chronic parkinsonism model
Villadiego Luque, Francisco Javier; Labrador Garrido, Adahir; Franco, Jaime M.; Leal Lasarte, Magdalena; Genst, Erwin J. de; Dobson, Christopher M.; Pozo Pérez, David; Toledo Aral, Juan José; Roodveldt, Cintia (Wiley, 2018)Neuroinflammation mediated by chronically activated microglia, largely caused by abnormal accumulation of misfolded ...
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Artículo
MAPK/MAK/MRK overlapping kinase (MOK) controls microglial inflammatory/type- I IFN responses via Brd4 and is involved in ALS
Pérez Cabello, Jesús; Silvera Carrasco, Lucía; Franco, Jaime M.; Capilla González, Vivian; García García, Raquel; Pozo Pérez, David; Roodveldt, Cintia (National Academy of Sciences, 2023)Amyotrophic lateral sclerosis (ALS) is a fatal and incurable neurodegenerative disease affecting motor neurons and ...
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Tesis Doctoral
Novel molecular mechanisms and signaling pathways of microglial responses in amyotrophic lateral sclerosis (ALS)
Leal Lasarte, María Magdalena (2019-05-22) -
Artículo
Preconditioning of Microglia by α-Synuclein Strongly Affects the Response Induced by Toll-like Receptor (TLR) Stimulation
Roodveldt, Cintia; Labrador Garrido, Adahir; González Rey, Elena; Lachaud, Christian; Guilliams, Tim; Fernández Montesinos, Rafael; Benítez Rondan, Alicia; Robledo, Gema; Hmadcha, Abdelkrim; Delgado, Mario; Dobson, Christopher M.; Pozo, D. (PLOS, 2013)In recent years, it has become accepted that α-synuclein (αSyn) has a key role in the microglia-mediated neuroinflammation, ...