Listar Artículos (Instituto de Investigaciones Químicas (IIQ) – CIC Cartuja) por agencia financiadora "Universidad de Sevilla"
Mostrando ítems 1-12 de 12
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A putative RNA binding protein from Plasmodium vivax apicoplast
(Wiley, 2018)Malaria is caused by Apicomplexa protozoans from the Plasmodium genus entering the bloodstream of humans and animals through ...
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Biodegradable particles for protein delivery: estimation of the release kinetics inside cells
(Elsevier, 2022-08)A methodology to quantify the efficiency of the protein loading and in-vitro delivery for biodegradable capsules with ...
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Biological Evaluation of Carbohydrate-based Aprepitant Analogs for Neuroblastoma Treatment
(Elsevier, 2024)Different studies using Aprepitant, a NK1R antagonist currently used as a clinical drug for treating chemotherapy-related ...
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Chirality influence on the cytotoxic properties of anionic chiral bis(N-heterocyclic carbene)silver complexes
(Elsevier, 2022)Complexes Na3[Ag(NHCR)2], 2a-e and 2b’-c’, where NHCR is a N-heterocyclic carbene of the 2,2′-(1H-2λ3,3λ4-imidazole-1,3-diyl)dicarboxylate ...
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Development of silica‐based biodegradable submicrometric carriers and investigating their characteristics as in vitro delivery vehicles
(MDPI, 2020)Nanostructured silica (SiO2)-based materials are attractive carriers for the delivery of bioactive compounds into cells. ...
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Exploring Multi-Subsite Binding Pockets in Proteins: DEEP-STD NMR Fingerprinting and Molecular Dynamics Unveil a Cryptic Subsite at the GM1 Binding Pocket of Cholera Toxin B
(Wiley, 2020)Ligand-based NMRtechniquesto studyprotein–ligandinteractionsare potenttoolsin drugdesign.Satura-tiontransfer difference ...
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Fluoro-labelled sp2-iminoglycolipids with immunomodulatory properties
(Elsevier, 2023)The unique electronic properties of the fluorine atom make its strategic incorporation into a bioactive compound a very ...
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Glycomimetic-based pharmacological chaperones for lysosomal storage disorders: lessons from Gaucher, GM1-gangliosidosis and Fabry diseases
(Royal Society of Chemistry, 2016)Lysosomal storage disorders (LSDs) are often caused by mutations that destabilize native folding and impair the trafficking ...
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Lysosomes: multifunctional compartments ruled by a complex regulatory network
(Wiley, 2022)More than 50 years have passed since Nobel laureate Cristian de Duve described for the first time the presence of tiny ...
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Reversible Light-Induced Dimerization of Secondary Face Azobenzene-Functionalized β-Cyclodextrin Derivatives
(American Chemical Society, 2023)β-cyclodextrin (βCyD) derivatives equipped with aromatic appendages at the secondary face exhibit tailorable self-assembling ...
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sp2-Iminosugars targeting human lysosomal β-hexosaminidase as pharmacological chaperone candidates for late-onset Tay-Sachs disease
(Taylor & Francis, 2022)The late-onset form of Tay-Sachs disease displays when the activity levels of human β-hexosaminidase A (HexA) fall below ...
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Zero-valent ML2complexes of Group 10 Metals Supported by Terphenyl Phosphanes
(Royal Society of Chemistry, 2021)Bulky terphenyl phosphane ligands PMe2Ar′ (Ar′ = terphenyl group) facilitate the isolation of zero-valent bis-phosphane ...