Listar Artículos (Instituto de Investigaciones Químicas (IIQ) – CIC Cartuja) por agencia financiadora "Ministerio de Economía y Competitividad (MINECO). España"
Mostrando ítems 1-20 de 66
-
Artículo
A Diels–Alder Reaction Triggered by a [4 + 3] Metallacycloaddition
(American Chemical Society, 2015)The TpMe2Ir(III) complex 1-OH2 (TpMe2 = hydrotris(3,5-dimethylpyrazolyl)borate), which contains a labile molecule of water ...
-
Artículo
A Dynamic Kinetic C-P Cross-Coupling for the Asymmetric Synthesis of Axially Chiral P,N Ligands
(American Chemical Society, 2016)The Pd-catalyzed enantioselective C-P cross-coupling between racemic, configurationally stable heterobiaryl triflates and ...
-
Artículo
Aluminium(iii) dialkyl 2,6-bisimino-4R-dihydropyridinates(−1): selective synthesis, structure and controlled dimerization
(Royal Society of Chemistry, 2019)A family of stable and otherwise selectively unachievable 2,6-bisimino-4-R-1,4-dihydropyridinate aluminium (III) dialkyl ...
-
Artículo
Asymmetric Organocatalytic Synthesis of Fluorinated β-Hydroxy Diazenes
(Wiley-Blackwell, 2019)The nucleophilic addition of formaldehyde tert-butyl hydrazone to fluoromethyl ketones provides a valuable tool for the ...
-
Artículo
AuI-Catalyzed Haloalkynylation of Alkenes
(Wiley-Blackwell, 2020)The formal insertion of alkenes into aromatic chloro- and bromoalkynes takes place under cationic gold catalysis. This ...
-
Artículo
Axially Chiral Triazoloisoquinolin-3-ylidene Ligands in Gold(I)-catalyzed Asymmetric Intermolecular (4 + 2) Cycloadditions of Allenamides and Dienes
(American Chemical Society, 2012)The first highly enantioselective intermolecular (4 + 2) cycloaddition between allenes and dienes is reported. The reaction ...
-
Artículo
Bifunctional Squaramide Organocatalysts for the Asymmetric Addition of Formaldehyde tert-Butylhydrazone to Simple Aldehydes
(Wiley-Blackwell, 2018)The nucleophilic addition of formaldehyde tert-butylhydrazone to simple aldehydes (a formal hetero-carbonyl–ene reaction) ...
-
Artículo
Catalytic amine-borane dehydrogenation by a PCP-pincer palladium complex: A combined experimental and DFT analysis of the reaction mechanism
(Royal Society of Chemistry (Great Britain), 2013)Catalytic dehydrogenation of ammonia-borane (NH3·BH 3, AB) and dimethylamine borane (NHMe2·BH 3, DMAB) by the PdII complex ...
-
Artículo
Cell uptake mechanisms of glycosylated cationic pDNA-cyclodextrin nanoparticles
(Royal Society of Chemistry, 2015)The incorporation of carbohydrate functional elements in the architecture of polycationic amphiphilic cyclodextrins (paCDs) ...
-
Artículo
Cyclodextrin-based facial amphiphiles: Assessing the impact of the hydrophilic-lipophilic balance in the self-assembly, DNA complexation and gene delivery capabilities
(Royal Society of Chemistry, 2016)Exhaustive structure–efficacy relationship studies on nonviral gene delivery systems are often hampered by the ill-defined ...
-
Artículo
Cyclodextrin-based multivalent glycodisplays: Covalent and supramolecular conjugates to assess carbohydrate-protein interactions
(Royal Society of Chemistry (Great Britain), 2013)Covalent attachment of biorecognizable sugar ligands in several copies at precise positions of cyclomaltooligosaccharide ...
-
Artículo
Design, synthesis and biological studies of a library of NK1-Receptor Ligands Based on a 5-arylthiosubstituted 2-amino-4,6-diaryl-3-cyano-4H-pyran core: Switch from antagonist to agonist effect by chemical modification
(Elsevier, 2017)A library of 5-arylthiosubstituted 2-amino-4,6-diaryl-3-cyano-4H-pyrans has been synthesized as a new family of non-peptide ...
-
Artículo
Development of silica‐based biodegradable submicrometric carriers and investigating their characteristics as in vitro delivery vehicles
(MDPI, 2020)Nanostructured silica (SiO2)-based materials are attractive carriers for the delivery of bioactive compounds into cells. ...
-
Artículo
Direct evidence for a coordination-insertion mechanism of ethylene oligomerization catalysed by neutral 2,6-bisiminopyridine iron monoalkyl complexes
(Royal Society of Chemistry, 2014)1H NMR studies on ethylene oligomerization catalysed by the neutral monoalkyl complex [Fe(Me)(iPrBIP)] allow direct ...
-
Artículo
Double asymmetric hydrogenation of conjugated dienes: a self-breeding chirality route for C2 symmetric 1,4-diols
(Royal Society of Chemistry, 2019)The synthesis and double asymmetric hydrogenation of (Z,Z)-1,3- diene-1,4-diyl diacetates is described. In this reaction ...
-
Artículo
Evidence for Genuine Bimetallic Frustrated Lewis Pair Activation of Dihydrogen with Gold(I)/Platinum(0) Systems
(Wiley-Blackwell, 2020)A joint experimental/computational effort to elucidate the mechanism of dihydrogen activation by a gold(I)/platinum(0) ...
-
Artículo
Exploring Multi-Subsite Binding Pockets in Proteins: DEEP-STD NMR Fingerprinting and Molecular Dynamics Unveil a Cryptic Subsite at the GM1 Binding Pocket of Cholera Toxin B
(Wiley, 2020)Ligand-based NMRtechniquesto studyprotein–ligandinteractionsare potenttoolsin drugdesign.Satura-tiontransfer difference ...
-
Artículo
Functionalization of 3-Iridacyclopentenes
(Wiley, 2017)Members of a series of iridacyclopentenes of composition [TpMe2Ir(k2-C,C-CH2CR′=CRCH2)(CO)] (TpMe2=hydrotris(3,5-dimethylpyrazolyl)borate; ...
-
Artículo
Glycodendritic structures: Tools to interact with DC-SIGN
(Universidade de São Paulo, 2013)The key role of carbohydrates in many biological events has attracted the interest of the scientific community. This fact ...
-
Artículo
Glycomimetic-based pharmacological chaperones for lysosomal storage disorders: lessons from Gaucher, GM1-gangliosidosis and Fabry diseases
(Royal Society of Chemistry, 2016)Lysosomal storage disorders (LSDs) are often caused by mutations that destabilize native folding and impair the trafficking ...