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Tesis Doctoral
Síntesis química y enzimática de biofenoles lipofilos del olivo con actividad antiinflamatoria. Optimización de la reacción de Krapcho
(2017-09-15)
En la presente Tesis Doctoral se ha realizado la síntesis de una serie de compuestos lipófilos, a partir de biofenoles contenidos tanto en la hoja de olivo como en el aceite de oliva virgen extra (AOVE), bajo la hipótesis ...
Artículo
New tacrine dimers with antioxidant linkers as dual drugs: Anti-Alzheimer's and antiproliferative agents
(Elsevier, 2017)
We have designed a series of tacrine-based homo- and heterodimers that incorporate an antioxidant tether (selenoureido, chalcogenide) as new dual compounds: for the treatment of Alzheimer's disease and as antiproliferative ...
Artículo
Synthesis and Antiproliferative Activity of Sulfa-Michael Adducts and Thiochromenes Derived from Carbohydrates
(Royal Society of Chemistry, 2017)
The Michael addition reactions of carbohydrate-derived nitroalkenes with ethyl thioglycolate and 2-mercaptobenzyl alcohol were studied. Reactions were conducted under mild, solvent-free conditions with DABCO as a catalyst, ...