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ListarArtículos (Microbiología) por materia "FBXW7"

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      Loss of FBXW7 and accumulation of MCL1 and PLK1 promote paclitaxel resistance in breast cancer 

      Gasca, Jessica; Flores de Mera, María de la Luz; Giraldez Macias, Servando; Tortolero García, María Dolores; Ruiz-Borrego, Manuel; Romero Portillo, Francisco; Japón, Miguel A.; Sáez, Carmen (Impact Journals, 2016)
      FBXW7 is a component of SCF (complex of SKP1, CUL1 and F-box-protein)-type ubiquitin ligases that targets several oncoproteins ...
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      p53 and FBXW7: Sometimes Two Guardians Are Worse than One 

      Galindo Moreno, María; Giráldez Macías, Servando; Limón Mortés, María Cristina; Belmonte Fernández, Alejandro; Sáez, Carmen; Japón, Miguel Ángel; Tortolero García, María Dolores; Romero Portillo, Francisco (MDPI, 2020)
      Too much of a good thing can become a bad thing. An example is FBXW7, a well-known tumor suppressor that may also contribute ...
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      SCFFBXW7α modulates the intra-S-phase DNA-damage checkpoint by regulating Polo like kinase-1 stability 

      Giráldez Macías, Servando; Herrero Ruiz, Joaquín; Mora Santos, María del Mar; Japón, Miguel Ángel; Tortolero García, María Dolores; Romero Portillo, Francisco (Impact Journals LLC, 2014)
      The intra-S-checkpoint is essential to control cell progression through S phase under normal conditions and in response ...