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Mostrando ítems 11-20 de 114
Artículo
Effect of Glycerol on Fosfomycin Activity against Escherichia coli
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)
Fosfomycin is an antimicrobial that inhibits the biosynthesis of peptidoglycan by entering the bacteria through two channels (UhpT and GlpT). Glycerol is clinically used as a treatment for elevated intracranial pressure ...
Artículo
Interplay Among Different Fosfomycin Resistance Mechanisms in Klebsiella Pneumoniae
(American Society for Microbiology, 2021)
The objectives of this study were to characterize the role of the uhpT, glpT, and fosA genes in fosfomycin resistance in Klebsiella pneumoniae and evaluate the use of sodium phosphonoformate (PPF) in combination with ...
Tesis Doctoral
Heterorresistencia a fosfomicina en Escherichia coli: bases moleculares y efecto en su potencial terapéutico
(2022-03-15)
En las últimas décadas, el aumento progresivo de la resistencia a los antimicrobianos se ha convertido en un problema mundial de salud pública. Consecuencia de ello y de la escasez de nuevas moléculas efectivas para el ...
Artículo
Effectiveness of Fosfomycin for the Treatment of Multidrug-Resistant Escherichia coli Bacteremic Urinary Tract Infections A Randomized Clinical Trial
(Jama Nerwork Open, 2022)
Importance The consumption of broad-spectrum drugs has increased as a consequence of the spread of multidrug-resistant (MDR) Escherichia coli. Finding alternatives for these infections is critical, for which some neglected ...
Tesis Doctoral
Mecanismos de resistencia a Carbapenemas en cepas clínicas de Acinetobacter baumannii
(2001-04-25)
En los últimos años se ha producido un incremento significativo en el número de infecciones nosocomiales causadas por cepas de Acinetobacter baumannii resistentes a carbapenemas. Las opciones terapéuticas en el tratamiento ...
Artículo
Intestinal colonization due to Escherichia coli ST131: Risk factors and prevalence
(Biomed Central, 2018-11-15)
Background Escherichia coli sequence type 131 (ST131) is a successful clonal group that has dramatically spread during the last decades and is considered an important driver for the rapid increase of quinolone resistance ...
Artículo
Nationwide study of Escherichia coli and Klebsiella pneumoniae producing extended-spectrum β-lactamases in Spain
(American Society for Microbiology, 2005-05-01)
Clonal dissemination of extended-spectrum -lactamases (ESBL) in 170 Escherichia coli isolates and 70 Klebsiella pneumoniae isolates from a nationwide study of 40 Spanish centers in 2000 was not observed in most centers. ...
Artículo
Uptake and intracellular activity of fluconazole in human polymorphonuclear leukocytes
(American Society for Microbiology, 1993-01-01)
The penetration of fluconazole into human polymorphonuclear leukocytes (PMNs) and tissue culture epithelial cells (McCoy) was evaluated. At different extracellular concentrations (0.5 to 10 mg/liter), fluconazole reached ...
Artículo
Prevalence, Incidence, and Risk Factors for Intestinal Colonization Due to Fluoroquinolone-Resistant ST131 Escherichia coli: a Longitudinal Study in Highly Dependent, Long-Term Care Facility Residents
(American Society for Microbiology, 2022)
Escherichia coli ST131 clade C is an important driver for fluoroquinolone resistance (FQ-R). We conducted a prospective observational study in residents from two long-term care facilities (LTCFs) in Seville, Spain, in 2018. ...
Artículo
Clinical Features of Infections and Colonization by Acinetobacter Genospecies 3
(American Society for Microbiology, 2010-12)
Two hundred twenty-one isolates of Acinetobacter baumannii and 15 of Acinetobacter genospecies 3 (AG3) were consecutively collected in a 30-day period during the nationwide project GEIH-Ab2000. Nosocomial acquisition (P = ...