Now showing items 11-16 of 16
The retrieval function of the KDEL receptor requires PKA phosphorylation of its C-terminus [Article]
(American Society for Cell Biology, 2003)
The KDEL receptor is a Golgi/intermediate compartment-located integral membrane protein that carries out the retrieval of escaped ER proteins bearing a C-terminal KDEL sequence. This occurs throughout retrograde traffic ...
Papel de los receptores de carga en la organización funcional de la ruta secretora temprana [Doctoral Thesis]
Introducción La organización estructural y funcional de la célula eucariota depende, en gran medida, de la actividad de la ruta secretora. Los procesos selectivos de transporte vesicular que operan a lo largo de esta ruta, ...
The yeast p24 complex is required for the formation of COPI retrograde transport vesicles from the Golgi apparatus [Article]
(Rockefeller University Press, 2008)
The p24 family members are transmembrane proteins assembled into heteromeric complexes that continuously cycle between the ER and the Golgi apparatus. These cargo proteins were assumed to play a structural role in COPI ...
Osh proteins regulate COPII-mediated vesicular transport of ceramide from the endoplasmic reticulum in budding yeast [Article]
(Company of Biologists Ltd, 2014)
Lipids synthesized at the endoplasmic reticulum (ER) are delivered to the Golgi by vesicular and non-vesicular pathways. ER-to-Golgi transport is crucial for maintaining the different membrane lipid composition and identities ...
Limited ER quality control for GPI-anchored proteins [Article]
(Rockefeller University Press, 2016)
Endoplasmic reticulum (ER) quality control mechanisms target terminally misfolded proteins for ER-associated degradation (ERAD). Misfolded glycophosphatidylinositol-anchored proteins (GPI-APs) are, however, generally poor ...
Endoplasmic Reticulum Export of GPI-Anchored Proteins [Article]
Protein export from the endoplasmic reticulum (ER) is an essential process in all eukaryotes driven by the cytosolic coat complex COPII, which forms vesicles at ER exit sites for transport of correctly assembled secretory ...