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Artículo
Poor Cognitive Agility Conservation in Obese Aging People
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)
Life expectancy has been boosted in recent decades at expenses of increasing the age-associated diseases. Dementia, for its incidence, stands out among the pathologies associated with aging. The exacerbated cognitive ...
Artículo
Predictive Cell Culture Time Evolution Based on Electric Models
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)
Obtaining cell concentration measurements from a culture assay by using bioimpedance is a very useful method that can be used to translate impedances to cell concentration values. The purpose of this study was to find a ...
Artículo
Osh proteins regulate COPII-mediated vesicular transport of ceramide from the endoplasmic reticulum in budding yeast
(Company of Biologists Ltd, 2014)
Lipids synthesized at the endoplasmic reticulum (ER) are delivered to the Golgi by vesicular and non-vesicular pathways. ER-to-Golgi transport is crucial for maintaining the different membrane lipid composition and identities ...
Artículo
LanB1 Cooperates With Kon-Tiki During Embryonic Muscle Migration in Drosophila
(Frontiers Media S.A., 2022)
Muscle development is a multistep process that involves cell specification, myoblast fusion, myotube migration, and attachment to the tendons. In spite of great efforts trying to understand the basis of these events, little ...
Artículo
GPI anchors: Regulated as needed
(Rockefeller University Press, 2023)
GPI anchoring is an essential post-translational modification in eukaryotes that links proteins to the plasma membrane. In this issue, Liu et al. (2023. J. Cell Biol.https://doi.org/10.1083/jcb.202208159) suggest, for the ...
Artículo
Topological Progression in Proliferating Epithelia Is Driven by a Unique Variation in Polygon Distribution
(Public Library of Science, 2013)
Morphogenesis is consequence of lots of small coordinated variations that occur during development. In proliferating stages, tissue growth is coupled to changes in shape and organization. A number of studies have analyzed ...
Artículo
Role of Chromatin Replication in Transcriptional Plasticity, Cell Differentiation and Disease
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)
Chromatin organization is essential to maintain a correct regulation of gene expression and establish cell identity. However, during cell division, the replication of the genetic material produces a global disorganization ...
Artículo
Therapeutic Approach to Alzheimer’s Disease: Current Treatments and New Perspectives
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)
Alzheimer’s disease (AD) is the most common cause of dementia. The pathophysiology of this disease is characterized by the accumulation of amyloid-β, leading to the formation of senile plaques, and by the intracellular ...
Artículo
Presynaptic Endoplasmic Reticulum Architecture and Hereditary Spastic Paraplegia
(Wolters Kluwer Health, 2024)
Artículo
CartoCell, a high-content pipeline for 3D image analysis, unveils cell morphology patterns in epithelia
(Elsevier, 2023)
Decades of research have not yet fully explained the mechanisms of epithelial self-organization and 3D packing. Single-cell analysis of large 3D epithelial libraries is crucial for understanding the assembly and function ...