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Artículo
The yeast p24 complex regulates gpi-anchored protein Transport and quality control by monitoring anchor remodeling
(American Society for Cell Biology, 2011)
Glycosylphosphatidylinositol (GPI)-anchored proteins are secretory proteins that are attached to the cell surface of eukaryotic cells by a glycolipid moiety. Once GPI anchoring has occurred in the lumen of the endoplasmic ...
Artículo
Activation of the unfolded protein response pathway causes ceramide accumulation in yeast and INS-1E insulinoma cells
(Elsevier, 2012)
Sphingolipids are not only important components of membranes but also have functions in protein trafficking and intracellular signaling. The LCB1 gene encodes a subunit of the serine palmitoyltransferase, which is responsible ...
Artículo
Trafficking of glycosylphosphatidylinositol anchored proteins from the endoplasmic reticulum to the cell surface
(Elsevier, 2016)
In eukaryotes, many cell surface proteins are attached to the plasma membrane via a glycolipid glycosylphosphatidylinositol (GPI) anchor. GPI-anchored proteins (GPI-APs) receive the GPI anchor as a conserved posttranslational ...