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Mostrando ítems 1-10 de 17
Artículo
The Cockayne syndrome protein B is involved in the repair of 5-AZA-2′-deoxycytidine-induced DNA lesions
(Impact Journals, 2018)
The Cockayne Syndrome Protein B (CSB) plays an essential role in Transcription-Coupled Nucleotide Excision Repair (TC-NER) by recruiting repair proteins once transcription is blocked with a DNA lesion. In fact, CSB-deficient ...
Artículo
RENEB – Running the European Network of biological dosimetry and physical retrospective dosimetry
(Taylor & Francis, 2017)
Purpose: A European network was initiated in 2012 by 23 partners from 16 European countries with the aim to significantly increase individualized dose reconstruction in case of large-scale radiological emergency ...
Artículo
RENEB Inter-Laboratory Comparison 2021: The Dicentric Chromosome Assay
(Radiation Research Society, 2023)
After large-scale radiation accidents where many individuals are suspected to be exposed to ionizing radiation, biological and physical retrospective dosimetry assays are important tools to aid clinical decision making by ...
Artículo
Zebularine induces replication-dependent double-strand breaks which are preferentially repaired by homologous recombination
(Elsevier, 2017)
Zebularine is a second-generation, highly stable hydrophilic inhibitor of DNA methylation with oral bioavailability that preferentially target cancer cells. It acts primarily as a trap for DNA methyl transferases (DNMTs) ...
Artículo
The PARP inhibitor Olaparib disrupts base excision repair of 5-aza-2′-deoxycytidine lesions
(Oxford University Press, 2014)
Decitabine (5-aza-21-deoxycytidine, 5-azadC) is used in the treatment of Myelodysplatic syndrome (MDS) and Acute Myeloid Leukemia (AML). Its mechanism of action is thought to involve reactivation of genes implicated in ...
Artículo
Investigation of the influence of calibration practices on cytogenetic laboratory performance for dose estimation
(Taylor & Francis, 2017)
Purpose: In the frame of the QA program of RENEB, an inter-laboratory comparison (ILC) of calibration sources used in biological dosimetry was achieved to investigate the influence of calibration practices and protocols ...
Ponencia
Análisis de la posición de los item en relación con los índices de dificultad de los mismos
(Universidad Europea de Madrid, 2010)
Artículo
RENEB accident simulation exercise
(Taylor & Francis LTD, 2017)
Purpose: The RENEB accident exercise was carried out in order to train the RENEB participants in coordinating and managing potentially large data sets that would be generated in case of a major radiological event. Materials ...
Artículo
Integration of new biological and physical retrospective dosimetry methods into EU emergency response plans - joint RENEB and EURADOS inter-laboratory comparisons
(Taylor & Francis LTD, 2017)
Purpose: RENEB, ‘Realising the European Network of Biodosimetry and Physical Retrospective Dosimetry,’ is a network for research and emergency response mutual assistance in biodosimetry within the EU. Within this extremely ...
Artículo
Realización de seminarios a distancia mediante el uso de herramientas de blackboard (wimbaclassroom de webct) para conocer las aplicaciones y avances de los cultivos celulares en relación al ámbito laboral
(Red Estatal de Docencia Universitaria, 2010)
La asignatura de Cultivos Celulares impartida en la Licenciatura de Biología de la Universidad de Sevilla, proporciona a los alumnos información teórica y práctica en esta materia. El gran avance tecnológico de los ...