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      Oestrogen receptor β mediates the actions of bisphenol-A on ion channel expression in mouse pancreatic beta cells  [Article]

      Martínez-Pinna, Juan; Marroquí, Laura; Hmadcha, Abdelkrim; López Beas, Javier; Soriano, Sergi; Villar-Pazos, Sabrina; Alonso-Magdalena, Paloma; Santos, Reinaldo S. Dos; Quesada, Iván; Martin, Franz; Soria Escoms, Bernat (Springer Nature, 2019-09)
      Aims/hypothesis: Bisphenol-A (BPA) is a widespread endocrine-disrupting chemical that has been associated with type 2 diabetes development. Low doses of BPA modify pancreatic beta cell function and induce insulin resistance; ...
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      PAX4 preserves endoplasmic reticulum integrity preventing beta cell degeneration in a mouse model of type 1 diabetes mellitus  [Article]

      Mellado Gil, José Manuel; Jiménez Moreno, Carmen María; Martín Montalvo, Alejandro; Álvarez Mercado, Anabel; Fuente Martín, Esther; Cobo Vuilleumier, Nadia; Lorenzo, Petra Isabel; Gracia Herrera-Gómez, Irene de; López Noriega, Livia; Quesada, Iván; Gauthier, Benoit R. (Springer Nature, 2016)
      [Aims/hypothesis]: A strategy to enhance pancreatic islet functional beta cell mass (BCM) while restraining inflammation, through the manipulation of molecular and cellular targets, would provide a means to counteract the ...